Matthew G Gold
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Explore the profile of Matthew G Gold including associated specialties, affiliations and a list of published articles.
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25
Citations
799
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Recent Articles
1.
Dowsell R, Gold M
FEBS J
. 2025 Feb;
PMID: 39940106
Signal transduction of external primary signals into intracellular elevations of the second messenger cyclic AMP is an ancient and universal regulatory mechanism in biology. In mammals, 9 of the 10...
2.
Wee R, Mishchanchuk K, AlSubaie R, Church T, Gold M, MacAskill A
Neuron
. 2023 Nov;
112(2):288-305.e7.
PMID: 37977151
Hunger is an internal state that not only invigorates feeding but also acts as a contextual cue for higher-order control of anticipatory feeding-related behavior. The ventral hippocampus is crucial for...
3.
Curtis A, Zhu J, Penny C, Gold M
Elife
. 2023 Jul;
12.
PMID: 37489746
Ca/calmodulin-dependent protein kinase II (CaMKII) is essential for long-term potentiation (LTP) of excitatory synapses that is linked to learning and memory. In this study, we focused on understanding how interactions...
4.
Curtis A, Dowsell R, Gold M
Methods Mol Biol
. 2022 Mar;
2483:15-31.
PMID: 35286667
Protein Kinase A (PKA) is the major intracellular receptor for cAMP. Research into this prototype kinase is supported by kinase assays that are typically performed in vitro using radio-labeled ATP....
5.
Church T, Tewatia P, Hannan S, Antunes J, Eriksson O, Smart T, et al.
Elife
. 2021 Oct;
10.
PMID: 34612814
Interplay between the second messengers cAMP and Ca is a hallmark of dynamic cellular processes. A common motif is the opposition of the Ca-sensitive phosphatase calcineurin and the major cAMP...
6.
Ivica J, Lape R, Jazbec V, Yu J, Zhu H, Gouaux E, et al.
J Biol Chem
. 2021 Feb;
296:100387.
PMID: 33617876
Like other pentameric ligand-gated channels, glycine receptors (GlyRs) contain long intracellular domains (ICDs) between transmembrane helices 3 and 4. Structurally characterized GlyRs are generally engineered to have a very short...
7.
Church T, Gold M
Methods Mol Biol
. 2020 Oct;
2188:243-257.
PMID: 33119855
Cultured hippocampal slices from rodents, in which the architecture and functional properties of the hippocampal network are largely preserved, have proved to be a powerful substrate for studying healthy and...
8.
Gold M
Biochem Soc Trans
. 2019 Nov;
47(5):1355-1366.
PMID: 31671183
cAMP-dependent protein kinase (PKA) plays a central role in important biological processes including synaptic plasticity and sympathetic stimulation of the heart. Elevations of cAMP trigger release of PKA catalytic (C)...
9.
Coombs I, Soto D, McGee T, Gold M, Farrant M, Cull-Candy S
Nat Commun
. 2019 Sep;
10(1):4312.
PMID: 31541113
Desensitization is a canonical property of ligand-gated ion channels, causing progressive current decline in the continued presence of agonist. AMPA-type glutamate receptors (AMPARs), which mediate fast excitatory signaling throughout the...
10.
Sailer C, Offensperger F, Julier A, Kammer K, Walker-Gray R, Gold M, et al.
Nat Commun
. 2018 Oct;
9(1):4441.
PMID: 30361475
Deregulation of the ubiquitin ligase E6AP is causally linked to the development of human disease, including cervical cancer. In complex with the E6 oncoprotein of human papillomaviruses, E6AP targets the...