Matthew B Murphy
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Explore the profile of Matthew B Murphy including associated specialties, affiliations and a list of published articles.
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25
Citations
990
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Recent Articles
1.
Centeno C, Ghattas J, Dodson E, Steinmetz N, Murphy M, Berger D
Sci Rep
. 2025 Feb;
15(1):7244.
PMID: 40021765
Autologous bone marrow concentrate (BMC), platelet-rich plasma (PRP), and platelet lysate (PL) have emerged as promising orthobiologic treatment options for knee osteoarthritis (OA). The present observational study reports minimal clinically...
2.
Subati T, Kim K, Yang Z, Murphy M, Van Amburg J, Christopher I, et al.
Circ Arrhythm Electrophysiol
. 2025 Feb;
:e013199.
PMID: 39989351
Background: The strongest genetic risk factors for atrial fibrillation (AF) are DNA variants on chromosome 4q25 near the transcription factor gene . Mice deficient in () have increased AF susceptibility,...
3.
Subati T, Yang Z, Murphy M, Stark J, Trykall D, Davies S, et al.
Cells
. 2024 Mar;
13(6.
PMID: 38534327
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, yet the cellular and molecular mechanisms underlying the AF substrate remain unclear. Isolevuglandins (IsoLGs) are highly reactive lipid dicarbonyl products...
4.
Murphy M, Yang Z, Subati T, Farber-Eger E, Kim K, Blackwell D, et al.
Cardiovasc Res
. 2024 Feb;
120(8):899-913.
PMID: 38377486
Aims: The lymphocyte adaptor protein (LNK) is a negative regulator of cytokine and growth factor signalling. The rs3184504 variant in SH2B3 reduces LNK function and is linked to cardiovascular, inflammatory,...
5.
Agrawal V, Kropski J, Gokey J, Kobeck E, Murphy M, Murray K, et al.
Circ Res
. 2023 Nov;
133(11):885-898.
PMID: 37929582
Background: Pulmonary hypertension (PH) in heart failure with preserved ejection fraction (HFpEF) is a common and highly morbid syndrome, but mechanisms driving PH-HFpEF are poorly understood. We sought to determine...
6.
Murphy M, Kannankeril P, Murray K
Front Physiol
. 2023 Apr;
14:1149023.
PMID: 37113690
Atrial fibrillation (AF) is the most common human arrhythmia and is associated with increased risk of stroke, dementia, heart failure, and death. Among several animal models that have been used...
7.
Murphy M, Kim K, Kannankeril P, Murray K
J Vis Exp
. 2022 Jul;
(184).
PMID: 35848836
Mouse models of genetic and acquired risk factors for atrial fibrillation (AF) have proven valuable in investigating the molecular determinants of AF. Programmed electrical stimulation can be performed using transesophageal...
8.
Atluri S, Murphy M, Dragella R, Herrera J, Boachie-Adjei K, Bhati S, et al.
Pain Physician
. 2022 Mar;
25(2):193-207.
PMID: 35322978
Background: Regenerative medicine interventions are applied to assist in the repair, and to potentially replace or restore damaged tissue through the use of autologous/allogenic biologics and it continues to expand....
9.
Yang Z, Subati T, Kim K, Murphy M, Dougherty O, Christopher I, et al.
Circ Arrhythm Electrophysiol
. 2022 Feb;
15(3):e010636.
PMID: 35212578
Background: With aging, the human atrium invariably develops amyloid composed of ANP (atrial natriuretic peptide) and BNP (B-type natriuretic peptide). Preamyloid oligomers are the primary cytotoxic species in amyloidosis, and...
10.
Murphy M, Kim K, Kannankeril P, Subati T, Van Amburg J, Barnett J, et al.
Am J Physiol Heart Circ Physiol
. 2021 Nov;
322(1):H36-H43.
PMID: 34767487
Mice are routinely used to investigate molecular mechanisms underlying the atrial fibrillation (AF) substrate. We sought to optimize transesophageal rapid atrial pacing (RAP) protocols for the detection of AF susceptibility...