Joseph C Van Amburg
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Explore the profile of Joseph C Van Amburg including associated specialties, affiliations and a list of published articles.
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7
Citations
41
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Recent Articles
1.
Subati T, Kim K, Yang Z, Murphy M, Van Amburg J, Christopher I, et al.
Circ Arrhythm Electrophysiol
. 2025 Feb;
:e013199.
PMID: 39989351
Background: The strongest genetic risk factors for atrial fibrillation (AF) are DNA variants on chromosome 4q25 near the transcription factor gene . Mice deficient in () have increased AF susceptibility,...
2.
Parker A, Van Amburg J, Van Amburg J, Heimlich J, Pershad Y, Mickels N, et al.
Blood
. 2024 Nov;
145(9):988-992.
PMID: 39565983
We have developed a cost-effective DNA methylation sequencing assay to improve monitoring of clonal hematopoiesis. By inferring cell-type proportions, this method enhances interpretation of clonal trajectories compared with interpretation based...
3.
Mack T, Pershad Y, Vlasschaert C, Bejan C, Heimlich J, Li Y, et al.
Haematologica
. 2024 Nov;
PMID: 39540221
Not available.
4.
Heimlich J, Bhat P, Parker A, Jenkins M, Vlasschaert C, Ulloa J, et al.
Blood Adv
. 2024 Mar;
8(14):3665-3678.
PMID: 38507736
Clonal hematopoiesis (CH) is an age-associated phenomenon that increases the risk of hematologic malignancy and cardiovascular disease. CH is thought to enhance disease risk through inflammation in the peripheral blood.1...
5.
Vlasschaert C, Robinson-Cohen C, Chen J, Akwo E, Parker A, Silver S, et al.
Nat Med
. 2024 Mar;
30(3):810-817.
PMID: 38454125
Age is a predominant risk factor for acute kidney injury (AKI), yet the biological mechanisms underlying this risk are largely unknown. Clonal hematopoiesis of indeterminate potential (CHIP) confers increased risk...
6.
Murphy M, Yang Z, Subati T, Farber-Eger E, Kim K, Blackwell D, et al.
Cardiovasc Res
. 2024 Feb;
120(8):899-913.
PMID: 38377486
Aims: The lymphocyte adaptor protein (LNK) is a negative regulator of cytokine and growth factor signalling. The rs3184504 variant in SH2B3 reduces LNK function and is linked to cardiovascular, inflammatory,...
7.
Chioma O, Mallott E, Chapman A, Van Amburg J, Wu H, Shah-Gandhi B, et al.
Commun Biol
. 2022 Dec;
5(1):1401.
PMID: 36543914
Independent studies demonstrate the significance of gut microbiota on the pathogenesis of chronic lung diseases; yet little is known regarding the role of the gut microbiota in lung fibrosis progression....
8.
Yang Z, Subati T, Kim K, Murphy M, Dougherty O, Christopher I, et al.
Circ Arrhythm Electrophysiol
. 2022 Feb;
15(3):e010636.
PMID: 35212578
Background: With aging, the human atrium invariably develops amyloid composed of ANP (atrial natriuretic peptide) and BNP (B-type natriuretic peptide). Preamyloid oligomers are the primary cytotoxic species in amyloidosis, and...
9.
Murphy M, Kim K, Kannankeril P, Subati T, Van Amburg J, Barnett J, et al.
Am J Physiol Heart Circ Physiol
. 2021 Nov;
322(1):H36-H43.
PMID: 34767487
Mice are routinely used to investigate molecular mechanisms underlying the atrial fibrillation (AF) substrate. We sought to optimize transesophageal rapid atrial pacing (RAP) protocols for the detection of AF susceptibility...