Matthew A Bratkowski
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Explore the profile of Matthew A Bratkowski including associated specialties, affiliations and a list of published articles.
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4
Citations
156
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Recent Articles
1.
Liu J, Bratkowski M, Liu X, Niu C, Ke A, Wang H
Nat Struct Mol Biol
. 2013 Dec;
21(1):95-102.
PMID: 24336220
The eukaryotic exosome is a multisubunit complex typically composed of a catalytically inactive core and the Rrp44 protein, which contains 3'-to-5' exo- and endo-RNase activities. RNA substrates have been shown...
2.
Lee G, Bratkowski M, Ding F, Ke A, Ha T
Science
. 2012 Jun;
336(6089):1726-9.
PMID: 22745434
Rrp44 (Dis3) is a key catalytic subunit of the yeast exosome complex and can processively digest structured RNA one nucleotide at a time in the 3' to 5' direction. Its...
3.
Karlsson A, Lim H, Xu H, Rocco M, Bratkowski M, Ke A, et al.
J Mol Biol
. 2011 Dec;
416(1):94-107.
PMID: 22197376
A hallmark of the bacterial twin-arginine translocation (Tat) pathway is its ability to export folded proteins. Here, we discovered that overexpressed Tat substrate proteins form two distinct, long-lived translocation intermediates...
4.
Wang H, Wang J, Ding F, Callahan K, Bratkowski M, Butler J, et al.
Proc Natl Acad Sci U S A
. 2007 Oct;
104(43):16844-9.
PMID: 17942686
The eukaryotic core exosome (CE) is a conserved nine-subunit protein complex important for 3' end trimming and degradation of RNA. In yeast, the Rrp44 protein constitutively associates with the CE...