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Mats Ljungman

Explore the profile of Mats Ljungman including associated specialties, affiliations and a list of published articles. Areas
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Articles 127
Citations 3459
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Recent Articles
1.
Tsoi L, Dong Y, Patrick M, Sarkar M, Zhang H, Bogle R, et al.
Res Sq . 2025 Feb; PMID: 39975900
Inflammatory skin diseases (ISDs) exhibit varying prevalence across different ancestry background and geographical regions. Genetic research for complex ISDs has predominantly centered on European Ancestry (EurA) populations and genetic effects...
2.
Moore J, Pratt H, Fan K, Phalke N, Fisher J, Elhajjajy S, et al.
bioRxiv . 2025 Jan; PMID: 39763870
Mammalian genomes contain millions of regulatory elements that control the complex patterns of gene expression. Previously, The ENCODE consortium mapped biochemical signals across many cell types and tissues and integrated...
3.
van den Heuvel D, Rodriguez-Martinez M, van der Meer P, Nieto Moreno N, Park J, Kim H, et al.
Cell . 2024 Nov; 187(25):7107-7125.e25. PMID: 39547229
Transcription-coupled DNA repair (TCR) removes bulky DNA lesions impeding RNA polymerase II (RNAPII) transcription. Recent studies have outlined the stepwise assembly of TCR factors CSB, CSA, UVSSA, and transcription factor...
4.
Mehta G, Horst E, Cotter L, Bonini M, Novak C, Treacher N, et al.
Res Sq . 2024 Nov; PMID: 39483899
The accumulation of ascites in patients with ovarian cancer increases their risk of transcoelomic metastasis. Although common routes of peritoneal dissemination are known to follow distinct paths of circulating ascites,...
5.
Mittal P, Myers J, Carter R, Radko-Juettner S, Malone H, Rosikiewicz W, et al.
Nat Commun . 2024 Aug; 15(1):7303. PMID: 39181868
Genes encoding subunits of SWI/SNF (BAF) chromatin remodeling complexes are mutated in nearly 25% of cancers. To gain insight into the mechanisms by which SWI/SNF mutations drive cancer, we contributed...
6.
van den Heuvel D, Rodriguez-Martinez M, van der Meer P, Nieto Moreno N, Park J, Kim H, et al.
bioRxiv . 2024 Aug; PMID: 39091731
Transcription-coupled DNA repair (TCR) removes bulky DNA lesions impeding RNA polymerase II (RNAPII) transcription. Recent studies have outlined the stepwise assembly of TCR factors CSB, CSA, UVSSA, and TFIIH around...
7.
Bedi K, Magnuson B, Narayanan I, McShane A, Ashaka M, Paulsen M, et al.
bioRxiv . 2024 Jun; PMID: 38915566
Steady-state levels of RNA transcripts are controlled by their rates of synthesis and degradation. Here we used nascent RNA Bru-seq and BruChase-seq to profile RNA dynamics across 16 human cell...
8.
McShane A, Narayanan I, Paulsen M, Ashaka M, Blinkiewicz H, Yang N, et al.
bioRxiv . 2024 Apr; PMID: 38645116
Arising as co-products of canonical gene expression, transcription-associated lincRNAs, such as promoter upstream transcripts (PROMPTs), enhancer RNAs (eRNAs), and readthrough (RT) transcripts, are often regarded as byproducts of transcription, although...
9.
Nunez F, Banerjee K, Mujeeb A, Mauser A, Tronrud C, Zhu Z, et al.
bioRxiv . 2024 Apr; PMID: 38559270
One Sentence Summary: The inhibition of autophagy sensitizes mIDH1 glioma cells to radiation, thus creating a promising therapeutic strategy for mIDH1 glioma patients. Graphical Abstract: Our genetically engineered mIDH1 mouse...
10.
Sharma M, Barravecchia I, Teis R, Cruz J, Mumby R, Ziemke E, et al.
Mol Cancer Ther . 2023 Sep; 23(1):24-34. PMID: 37723046
Therapeutic resistance remains a major obstacle to successful clinical management of diffuse intrinsic pontine glioma (DIPG), a high-grade pediatric tumor of the brain stem. In nearly all patients, available therapies...