Matilde Clarissa Malfatti
Overview
Explore the profile of Matilde Clarissa Malfatti including associated specialties, affiliations and a list of published articles.
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19
Citations
288
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Recent Articles
1.
Bellina A, Malfatti M, Salgado G, Fleming A, Antoniali G, Othman Z, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(46):e2317861121.
PMID: 39495925
In the last decade, several novel functions of the mammalian Apurinic/Apyrimidinic Endodeoxyribonuclease 1 (APE1) have been discovered, going far beyond its canonical function as DNA repair enzyme and unveiling its...
2.
Furlani F, Malfatti M, Rondinella A, Campodoni E, Sandri M, Fedrizzi L, et al.
J Biol Eng
. 2024 Oct;
18(1):60.
PMID: 39456111
Hydroxyapatite (HA) is a bioceramic material widely used as a bone biomimetic substitute and can be synthesized by biomineralization, according to which HA nanoparticles are formed on a polymer template....
3.
Malfatti M, Antoniali G, Tell G
Methods Mol Biol
. 2023 Aug;
2701:21-38.
PMID: 37574473
APE1 (apurinic/apyrimidinic endodeoxyribonuclease 1) is a central enzyme of the base excision repair (BER) pathway playing a pivotal role in protecting mammalian cells against genotoxins and in safeguarding genome stability....
4.
Malfatti M, Bellina A, Antoniali G, Tell G
Cells
. 2023 Jul;
12(14).
PMID: 37508559
APE1 is an essential endodeoxyribonuclease of the base excision repair pathway that maintains genome stability. It was identified as a pivotal factor favoring tumor progression and chemoresistance through the control...
5.
DallAgnese G, DallAgnese A, Banani S, Codrich M, Malfatti M, Antoniali G, et al.
J Biol Chem
. 2023 May;
299(6):104800.
PMID: 37164156
For cells, it is important to repair DNA damage, such as double-strand and single-strand DNA breaks, because unrepaired DNA can compromise genetic integrity, potentially leading to cell death or cancer....
6.
Malfatti M, Codrich M, Dalla E, DAmbrosio C, Storici F, Scaloni A, et al.
Antioxid Redox Signal
. 2023 Mar;
39(7-9):411-431.
PMID: 36855946
The existence of modified ribonucleotide monophosphates embedded in genomic DNA, as a consequence of oxidative stress conditions, including 8-oxo-guanosine and ribose monophosphate abasic site (rAP), has been recently highlighted by...
7.
Codrich M, Degrassi M, Malfatti M, Antoniali G, Gorassini A, Ayyildiz D, et al.
FEBS J
. 2022 Oct;
290(7):1740-1764.
PMID: 36310106
The nuclear RNA surveillance mechanism is essential for cancer cell survival and is ensured by the RNA nuclear exosome including some co-factors, such as the RNA helicase MTR4. Recent studies...
8.
Beltrami A, De Martino M, Dalla E, Malfatti M, Caponnetto F, Codrich M, et al.
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012423
The persistence of long-term coronavirus-induced disease 2019 (COVID-19) sequelae demands better insights into its natural history. Therefore, it is crucial to discover the biomarkers of disease outcome to improve clinical...
9.
Codrich M, Dalla E, Mio C, Antoniali G, Malfatti M, Marzinotto S, et al.
J Exp Clin Cancer Res
. 2021 Jun;
40(1):198.
PMID: 34154611
Background: Colorectal cancer (CRC) represents the fourth leading cause of cancer-related deaths. The heterogeneity of CRC identity limits the usage of cell lines to study this type of tumor because...
10.
Malfatti M, Antoniali G, Codrich M, Tell G
DNA Repair (Amst)
. 2021 May;
104:103133.
PMID: 34049077
Interest in RNA damage as a novel threat associated with several human pathologies is rapidly increasing. Knowledge on damaged RNA recognition, repair, processing and decay is still scanty. Interestingly, in...