Mathieu Danoy
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Explore the profile of Mathieu Danoy including associated specialties, affiliations and a list of published articles.
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26
Citations
107
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Recent Articles
11.
Danoy M, Tauran Y, Poulain S, Jellali R, Bruce J, Leduc M, et al.
APL Bioeng
. 2021 May;
5(2):026104.
PMID: 34027283
Interactions between the different liver cell types are critical to the maintenance or induction of their function . In this work, human-induced Pluripotent Stem Cells (hiPSCs)-derived Liver Sinusoidal Endothelial Cells...
12.
Danoy M, Tauran Y, Poulain S, Jellali R, Bruce J, Leduc M, et al.
Biotechnol Bioeng
. 2021 Jan;
118(10):3716-3732.
PMID: 33404112
Maturation of human-induced pluripotent stem cells (hiPSCs)-derived hepatocytes-like cells (HLCs) toward a complete hepatocyte phenotype remains a challenge as primitiveness patterns are still commonly observed. In this study, we propose...
13.
Scheidecker B, Shinohara M, Sugimoto M, Danoy M, Nishikawa M, Sakai Y
Front Bioeng Biotechnol
. 2020 Jul;
8:524.
PMID: 32656187
Pre-clinical drug screening is an important step in assessing the metabolic effects and hepatic toxicity of new pharmaceutical compounds. However, due to the complexity of the liver microarchitecture, simplified models...
14.
Danoy M, Tauran Y, Poulain S, Arakawa H, Mori D, Araya K, et al.
Differentiation
. 2020 Jun;
114:36-48.
PMID: 32563741
The capability to produce and maintain functional human adult hepatocytes remains one of the major challenges for the use of in-vitro models toward liver cell therapy and industrial drug-screening applications....
15.
Essaouiba A, Okitsu T, Jellali R, Shinohara M, Danoy M, Tauran Y, et al.
Mol Cell Endocrinol
. 2020 Jun;
514:110892.
PMID: 32531418
Organ-on-chip technology is a promising tool for investigating physiological in vitro responses in drug screening development, and in advanced disease models. Within this framework, we investigated the behavior of rat...
16.
Danoy M, Poulain S, Lereau-Bernier M, Kato S, Scheidecker B, Kido T, et al.
Biotechnol Prog
. 2020 May;
36(5):e3013.
PMID: 32364651
The liver zonation is an important phenomenon characterized by a gradient of several functions along the liver acinus. However, this gradient remains difficult to reproduce in in-vitro conditions, making the...
17.
Danoy M, Poulain S, Koui Y, Tauran Y, Scheidecker B, Kido T, et al.
Mol Omics
. 2020 Jan;
16(2):138-146.
PMID: 31989141
Liver Sinusoidal Endothelial Cells (LSECs) are an important component of the liver as they compose the microvasculature which allows the supply of oxygen, blood, and nutrients. However, maintenance of these...
18.
Pang Y, Sutoko S, Wang Z, Horimoto Y, Montagne K, Horiguchi I, et al.
Med Eng Phys
. 2019 Dec;
76:69-78.
PMID: 31883633
In order to address the remaining issues of fragile structure and insufficient mass transfer faced in modular assembly-based liver tissue engineering, a Raschig ring-like hollowed micro-scaffold was proposed and fabricated...
19.
Jellali R, Lereau Bernier M, Tauran Y, Gilard F, Danoy M, Kido T, et al.
Differentiation
. 2019 Dec;
112:17-26.
PMID: 31869687
Human induced pluripotent stem cells (hiPSCs) are potentially an invaluable source of cells for regenerative medicine, disease modeling and drug discovery. However, the differentiation of hiPSCs into fully functional hepatocytes...
20.
Tauran Y, Poulain S, Lereau-Bernier M, Danoy M, Shinohara M, Segard B, et al.
Mol Omics
. 2019 Oct;
15(6):383-398.
PMID: 31612883
We investigated the human induced pluripotent stem cells (hiPSCs) during a sequential in vitro step-by-step differentiation into hepatocyte-like cells (HLCs) using nanoCAGE, a method for promoters, transcription factors, and transcriptome...