Eric Leclerc
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Explore the profile of Eric Leclerc including associated specialties, affiliations and a list of published articles.
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90
Citations
723
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Recent Articles
1.
Miura Y, Voican C, Sakai Y, Nishikawa M, Leclerc E
Toxicol Appl Pharmacol
. 2024 Dec;
495:117185.
PMID: 39631537
Metabolic dysfunction-associated steatotic liver disease (MASLD; formerly known as NAFLD) is a common liver disease worldwide and carries the risk of progressing to severe liver conditions, such as fibrosis and...
2.
Wang H, Danoy M, Gong Y, Utami T, Arakawa H, Kato Y, et al.
J Appl Toxicol
. 2024 Nov;
45(3):460-471.
PMID: 39506029
Nonalcoholic fatty liver disease (NAFLD) is one of the main causes of critical liver diseases leading to steatosis, steatohepatitis, fibrosis, and ultimately to liver cirrhosis and hepatic carcinoma. In this...
3.
Leclerc E, Pachkov M, Morisseau L, Tokito F, Legallais C, Jellali R, et al.
Mol Omics
. 2024 Nov;
20(10):654-665.
PMID: 39494575
Pancreatic β-cells are composed of different subtypes that play a key role in the control of insulin secretion and thereby control glucose homeostasis. differentiation of human induced pluripotent stem cells...
4.
Morisseau L, Tokito F, Lucas M, Poulain S, Kim S, Plaisance V, et al.
Gene
. 2024 Apr;
917:148441.
PMID: 38608795
Type 2 diabetes (T2D) is posing a serious public health concern with a considerable impact on human life and health expenditures worldwide. The disease develops when insulin plasma level is...
5.
Scheidecker B, Poulain S, Sugimoto M, Kido T, Kawanishi T, Miyajima A, et al.
Biofabrication
. 2024 Mar;
16(2).
PMID: 38447229
Availability of hepatic tissue for the investigation of metabolic processes is severely limited. While primary hepatocytes or animal models are widely used in pharmacological applications, a change in methodology towards...
6.
Messelmani T, Le Goff A, Soncin F, Souguir Z, Merlier F, Maubon N, et al.
J Biosci Bioeng
. 2023 Nov;
137(1):64-75.
PMID: 37973520
The liver is one of the main organs involved in the metabolism of xenobiotics and a key organ in toxicity studies. Prior to accessing the hepatocytes, xenobiotics pass through the...
7.
Morisseau L, Tokito F, Poulain S, Plaisance V, Pawlowski V, Kim S, et al.
Mol Omics
. 2023 Oct;
19(10):823.
PMID: 37800443
Correction for 'Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids' by Lisa Morisseau , , 2023, https://doi.org/10.1039/d3mo00050h.
8.
Morisseau L, Tokito F, Poulain S, Plaisance V, Pawlowski V, Kim S, et al.
Mol Omics
. 2023 Sep;
19(10):810-822.
PMID: 37698079
Since the identification of four different pancreatic β-cell subtypes and bi-hormomal cells playing a role in the diabetes pathogenesis, the search for models that mimics such cells heterogeneity became a...
9.
Madiedo-Podvrsan S, Sebillet L, Martinez T, Bacari S, Zhu F, Cattelin M, et al.
Toxicol In Vitro
. 2023 Jul;
92:105641.
PMID: 37437822
Animal models are considered prime study models for inhalation-like toxicity assessment. However, in light of animal experimentation reduction (3Rs), we developed and investigated an alternative in vitro method to study...
10.
Messelmani T, Le Goff A, Soncin F, Gilard F, Souguir Z, Maubon N, et al.
Toxicology
. 2023 May;
492:153550.
PMID: 37209942
Organ-on-chip technology is a promising in vitro approach recapitulating human physiology for the study of responses to drug exposure. Organ-on-chip cell cultures have paved new grounds for testing and understanding...