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Mate Dobrossy

Explore the profile of Mate Dobrossy including associated specialties, affiliations and a list of published articles. Areas
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Articles 26
Citations 184
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Recent Articles
1.
Schultke E, Pinzer B, Stampanoni M, Harsan L, Dobrossy M
Neurol Int . 2023 Jul; 15(3):896-907. PMID: 37489363
High-resolution imaging in small animal models of neurologic disease is a technical challenge. In a pilot project, we have explored a non-destructive synchrotron imaging technique for the 3D visualization of...
2.
Gardner W, Fuchs F, Durieux L, Bourgin P, Coenen V, Dobrossy M, et al.
Neuroscience . 2022 Jun; 498:31-49. PMID: 35750113
Major Depressive Disorder (MDD) is an affective disorder typically accompanied by sleep disturbances. Deep brain stimulation (DBS) of the medial forebrain bundle (MFB) is an emerging intervention for treatment-resistant depression,...
3.
Coenen V, Schlaepfer T, Sajonz B, Dobrossy M, Kaller C, Urbach H, et al.
Neuroimage Clin . 2020 Jan; 25:102165. PMID: 31954987
Background: Major depression (MD) and obsessive-compulsive disorder (OCD) are psychiatric diseases with a huge impact on individual well-being. Despite optimal treatment regiments a subgroup of patients remains treatment resistant and...
4.
Kaindlstorfer C, Stefanova N, Garcia J, Krismer F, Dobrossy M, Gobel G, et al.
PLoS One . 2019 Jun; 14(6):e0218130. PMID: 31181111
Background: Unresponsiveness to dopaminergic therapies is a key feature in the diagnosis of multiple system atrophy (MSA) and a major unmet need in the treatment of MSA patients caused by...
5.
Tomov N, Surchev L, Wiedenmann C, Dobrossy M, Nikkhah G
Exp Neurol . 2019 Apr; 318:135-144. PMID: 31028828
Inhibitors of cell cycle proteins are known to reduce glial activation and to be neuroprotective in a number of settings. In the context of intracerebral grafting, glial activation is documented...
6.
Capetian P, Azmitia L, Pauly M, Krajka V, Stengel F, Bernhardi E, et al.
Front Cell Neurosci . 2016 Nov; 10:245. PMID: 27822179
Direct reprogramming from somatic to neural cell types has become an alternative to induced pluripotent stem cells. Most protocols employ viral expression systems, posing the risk of random genomic integration....
7.
Buchele F, Dobrossy M, Hackl C, Jiang W, Papazoglou A, Nikkhah G
Neurobiol Dis . 2014 May; 68:112-25. PMID: 24780496
Following transplantation of foetal primary dopamine (DA)-rich tissue for neurorestaurative treatment of Parkinson's disease (PD), only 5-10% of the functionally relevant DAergic cells survive both in experimental models and in...
8.
Dobrossy M, Pruszak J
Methods Mol Biol . 2013 Sep; 1037:117-44. PMID: 24029933
The nervous system is characterized by its complex network of highly specialized cells that enable us to perceive stimuli from the outside world and react accordingly. The computational integration enabled...
9.
Lopez W, Nikkhah G, Kahlert U, Maciaczyk D, Bogiel T, Moellers S, et al.
Restor Neurol Neurosci . 2013 Jun; 31(5):579-95. PMID: 23777636
Purpose: The concept of transplantation of neuronal cells to treat Huntington's and Parkinson's diseases is based on the proven principle that dopaminergic and GABA-ergic progenitor neurons (from the human developing...
10.
Piroth T, Pauly M, Schneider C, Wittmer A, Mollers S, Dobrossy M, et al.
Cell Transplant . 2013 May; 23(8):995-1007. PMID: 23635602
Restorative cell therapy concepts in neurodegenerative diseases are aimed at replacing lost neurons. Despite advances in research on pluripotent stem cells, fetal tissue from routine elective abortions is still regarded...