Mate Dobrossy
Overview
Explore the profile of Mate Dobrossy including associated specialties, affiliations and a list of published articles.
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26
Citations
184
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Recent Articles
11.
Kahlert U, Maciaczyk D, Dai F, Claus R, Firat E, Doostkam S, et al.
J Neuropathol Exp Neurol
. 2012 Nov;
71(12):1086-99.
PMID: 23147506
In addition to intrinsic regulatory mechanisms, brain tumor stemlike cells (BTSCs), a small subpopulation of malignant glial tumor-derived cells, are influenced by environmental factors. Previous reports showed that lowering oxygen...
12.
Garcia J, Carlsson T, Dobrossy M, Nikkhah G, Winkler C
Brain Res
. 2012 Jul;
1470:119-29.
PMID: 22759908
Graft-induced dyskinesia (GID), covering a range of dystonic and choreiform involuntary movements, has been observed in some patients with Parkinson's disease (PD) after intracerebral cell transplantation. These dyskinesias have been...
13.
Pauly M, Piroth T, Dobrossy M, Nikkhah G
Front Cell Neurosci
. 2012 Apr;
6:16.
PMID: 22529778
In the basal ganglia circuitry, the striatum is a highly complex structure coordinating motor and cognitive functions and it is severely affected in Huntington's disease (HD) patients. Transplantation of fetal...
14.
Garcia J, Carlsson T, Dobrossy M, Nikkhah G, Winkler C
Exp Neurol
. 2011 Sep;
232(2):270-9.
PMID: 21946270
Graft-induced dyskinesia has emerged as a problematic side effect after transplantation of fetal dopamine cells into the striatum of patients with Parkinson's disease. These adverse effects of dystonic and choreatiform...
15.
Garcia J, Carlsson T, Dobrossy M, Nikkhah G, Winkler C
Neurobiol Dis
. 2011 May;
43(3):576-87.
PMID: 21600983
Fetal dopamine (DA) cell transplantation has shown to be efficient in reversing behavioral impairments associated with Parkinson's disease. However, the beneficial effects on motor behavior and L-DOPA-induced dyskinesia have varied...
16.
Capetian P, Dobrossy M, Winkler C, Prinz M, Nikkhah G
Semin Immunopathol
. 2011 May;
33(6):619-26.
PMID: 21533909
Grafting of neural stem cells into the mammalian central nervous system (CNS) has been performed for some decades now, both in basic research and clinical applications for neurological disorders such...
17.
Mazzocchi-Jones D, Dobrossy M, Dunnett S
Neurorehabil Neural Repair
. 2011 Mar;
25(6):548-57.
PMID: 21444652
Background: Housing animals in an enriched environment improves motor and cognitive performance and anatomical connectivity in rodent lesion models of Huntington disease and transplantation of embryonic striatal grafts. Objective: The...
18.
Dobrossy M, Klein A, Janghra N, Nikkhah G, Dunnett S
J Neurosci Methods
. 2011 Feb;
197(1):6-13.
PMID: 21295605
Huntington's disease (HD) is a neurodegenerative disease with currently only symptomatic treatment. Cell-based therapy, aiming at replacing the lost medium spiny neurons (MSN) with primary fetal striatal cells, has had...
19.
Jiang W, Buchele F, Papazoglou A, Dobrossy M, Nikkhah G
Cell Transplant
. 2010 Dec;
20(10):1515-27.
PMID: 21176402
Embryonic striatal graft-mediated functional recovery in the rodent lesion model of Huntington's disease (HD) has been shown to correlate with the proportion of dopamine- and adenosine 3',5'-monophosphate-regulated phosphoprotein with a...
20.
Dobrossy M, Busse M, Piroth T, Rosser A, Dunnett S, Nikkhah G
Neurorehabil Neural Repair
. 2010 Jul;
24(8):692-701.
PMID: 20647502
Cell replacement therapy has been tested clinically in Parkinson's disease (PD) and Huntington's disease (HD), epilepsy, spinal cord injury, and stroke. The clinical outcomes have been variable, perhaps partly because...