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Massimo Ammirante

Explore the profile of Massimo Ammirante including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 1133
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Recent Articles
1.
Zhu D, Hadjivassiliou H, Jennings C, Mikolon D, Ammirante M, Acharya S, et al.
MAbs . 2024 Feb; 16(1):2310248. PMID: 38349008
Cluster of differentiation 47 (CD47) is a transmembrane protein highly expressed in tumor cells that interacts with signal regulatory protein alpha (SIRPα) and triggers a "don't eat me" signal to...
2.
Hansen J, Correa M, Alexander M, Nagy M, Huang D, Sapienza J, et al.
J Med Chem . 2021 Feb; 64(4):1835-1843. PMID: 33591756
Acute myeloid leukemia (AML) is marked by significant unmet clinical need due to both poor survival and high relapse rates where long-term disease control for most patients with relapsed or...
3.
Shalapour S, Font-Burgada J, Caro G, Zhong Z, Sanchez-Lopez E, Dhar D, et al.
Nature . 2015 Apr; 521(7550):94-8. PMID: 25924065
Cancer-associated genetic alterations induce expression of tumour antigens that can activate CD8(+) cytotoxic T cells (CTLs), but the microenvironment of established tumours promotes immune tolerance through poorly understood mechanisms. Recently...
4.
Ammirante M, Shalapour S, Kang Y, Jamieson C, Karin M
Proc Natl Acad Sci U S A . 2014 Oct; 111(41):14776-81. PMID: 25267627
Prostate cancer (PC) is a slowly progressing malignancy that often responds to androgen ablation or chemotherapy by becoming more aggressive, acquiring a neuroendocrine phenotype, and undergoing metastatic spread. We found...
5.
Woo J, Liss M, Muldong M, Palazzi K, Strasner A, Ammirante M, et al.
J Transl Med . 2014 Jan; 12:30. PMID: 24475900
Background: The presence of increased B-cell tumor infiltrating lymphocytes (TILs) was seen in mouse prostate cancer (PCa) but has not been fully documented in human PCa. We, therefore, investigated the...
6.
Ammirante M, Kuraishy A, Shalapour S, Strasner A, Ramirez-Sanchez C, Zhang W, et al.
Genes Dev . 2013 Jun; 27(13):1435-40. PMID: 23796898
Androgen-deprived prostate cancer (PCa) is infiltrated by B lymphocytes that produce cytokines that activate IκB kinase α (IKKα) to accelerate the emergence of castration-resistant tumors. We now demonstrate that infiltrating...
7.
Basile A, Zeppa R, Pasquino N, Arra C, Ammirante M, Festa M, et al.
J Cell Physiol . 2011 Feb; 226(11):2901-7. PMID: 21302292
The expression of the anti-apoptotic protein BAG3 is induced in several cell types by exposure to high temperature, oxidants, and other stressful agents. We investigated whether exposure to 50 Hz...
8.
Ammirante M, Rosati A, Arra C, Basile A, Falco A, Festa M, et al.
Proc Natl Acad Sci U S A . 2010 Apr; 107(16):7497-502. PMID: 20368414
BAG3, a member of the BAG family of heat shock protein (HSP) 70 cochaperones, is expressed in response to stressful stimuli in a number of normal cell types and constitutively...
9.
Ammirante M, Luo J, Grivennikov S, Nedospasov S, Karin M
Nature . 2010 Mar; 464(7286):302-5. PMID: 20220849
Prostate cancer (CaP) progresses from prostatic intraepithelial neoplasia through locally invasive adenocarcinoma to castration-resistant metastatic carcinoma. Although radical prostatectomy, radiation and androgen ablation are effective therapies for androgen-dependent CaP, metastatic...
10.
Rosati A, Ammirante M, Gentilella A, Basile A, Festa M, Pascale M, et al.
Int J Biochem Cell Biol . 2007 May; 39(7-8):1337-42. PMID: 17493862
Stress-induced apoptosis regulates neoplasia pathogenesis and response to therapy. Indeed, cell transformation induces a stress response, that is overcome, in neoplastic cells, by alterations in apoptosis modulators; on the other...