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Masoud Shekarabi

Explore the profile of Masoud Shekarabi including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 980
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Recent Articles
1.
Shekarabi M, Robinson J, Burdo T
Methods Mol Biol . 2021 May; 2311:177-184. PMID: 34033086
Preparations of peripheral sensory neurons from rodents are essential for studying the molecular mechanism of neuronal survival and physiology. Although, isolating and culturing these neurons proves difficult, often these preparations...
2.
Torkzaban B, Natarajaseenivasan K, Mohseni Ahooyi T, Shekarabi M, Amini S, Langford T, et al.
Cell Death Dis . 2020 Oct; 11(10):835. PMID: 33033233
HIV-1 Tat is a potent neurotoxic protein that is released by HIV-1 infected cells in the brain and perturbs neuronal homeostasis, causing a broad range of neurological disorders in people...
3.
Robinson J, Guenthner G, Warfield R, Kublin J, Smith M, Shekarabi M, et al.
Am J Pathol . 2020 Apr; 190(7):1530-1544. PMID: 32246920
HIV-associated sensory neuropathy is a common neurologic comorbidity of HIV infection and prevails in the post-antiretroviral therapy (ART) era. HIV infection drives pathologic changes in the dorsal root ganglia (DRG)...
4.
Shekarabi M, Robinson J, Smith M, Burdo T
J Neurosci . 2019 Jul; 39(35):7006-7018. PMID: 31270156
Although the reduction of viral loads in people with HIV undergoing combination antiretroviral therapy has mitigated AIDS-related symptoms, the prevalence of neurological impairments has remained unchanged. HIV-associated CNS dysfunction includes...
5.
Mohseni Ahooyi T, Torkzaban B, Shekarabi M, Tahrir F, Decoppet E, Cotto B, et al.
Cell Death Dis . 2019 Jun; 10(7):473. PMID: 31209204
HIV-1 Tat is known to be released by HIV infected non-neuronal cells in the brain, and after entering neurons, compromises brain homeostasis by impairing pro-survival pathways, thus contributing to the...
6.
Abu-Baker A, Kharma N, Perreault J, Grant A, Shekarabi M, Maios C, et al.
Mol Ther Nucleic Acids . 2019 Mar; 15:12-25. PMID: 30831428
Oculopharyngeal muscular dystrophy (OPMD) is caused by a small expansion of a short polyalanine (polyAla) tract in the poly(A)-binding protein nuclear 1 protein (PABPN1). Despite the monogenic nature of OPMD,...
7.
Mohseni Ahooyi T, Shekarabi M, Torkzaban B, Langford T, Burdo T, Gordon J, et al.
Sci Rep . 2018 Nov; 8(1):16300. PMID: 30390000
HIV-1 Tat protein is released from HIV-1-infected cells and can enter non-permissive cells including neurons. Tat disrupts neuronal homeostasis and may contribute to the neuropathogenesis in people living with HIV...
8.
Kearns A, Robinson J, Shekarabi M, Liu F, Qin X, Burdo T
J Neurovirol . 2018 Apr; 24(4):420-431. PMID: 29611111
In the antiretroviral therapy (ART) era, chronic HIV infection is primarily associated with chronic inflammation driving comorbidities such as cardiovascular disease and neurocognitive impairment. Caspase-1 activation in leukocytes has been...
9.
Mohseni Ahooyi T, Shekarabi M, Decoppet E, Langford D, Khalili K, Gordon J
J Cell Physiol . 2017 Dec; 233(12):9299-9311. PMID: 29206302
HIV-associated neurocognitive disorders affecting greater than 30% of patients are caused by HIV-1 infection of the CNS, and in part, include neurotoxic effects of the viral transactivator of transcription, Tat...
10.
Shekarabi M, Zhang J, Khanna A, Ellison D, Delpire E, Kahle K
Cell Metab . 2017 Feb; 25(2):285-299. PMID: 28178566
WNK kinases, along with their upstream regulators (CUL3/KLHL3) and downstream targets (the SPAK/OSR1 kinases and the cation-Cl cotransporters [CCCs]), comprise a signaling cascade essential for ion homeostasis in the kidney...