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Masaki Ohmuraya

Explore the profile of Masaki Ohmuraya including associated specialties, affiliations and a list of published articles. Areas
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Articles 89
Citations 5592
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Recent Articles
11.
Yamamoto T, Sano R, Miura A, Imasaka M, Naito Y, Nishiguchi M, et al.
J Mol Med (Berl) . 2022 Oct; 100(12):1741-1754. PMID: 36198914
RBM20 is one of the genes predisposing to dilated cardiomyopathy (DCM). Variants in the RS domain have been reported in many DCM patients, but the pathogenicity of variants within the...
12.
Chen W, Imasaka M, Iwama H, Nishiura H, Ohmuraya M
Pancreatology . 2022 Aug; 22(7):880-886. PMID: 36038449
Background: Premature intracellular trypsinogen activation has long been considered a key initiator of acute pancreatitis (AP). Cathepsin B (CTSB) activates trypsinogen, while cathepsin L (CTSL) inactivates trypsin(ogen), and both proteins...
13.
Yamazaki S, Inohara N, Ohmuraya M, Tsuneoka Y, Yagita H, Katagiri T, et al.
Mucosal Immunol . 2022 Aug; 15(6):1321-1337. PMID: 35999460
Control of gut microbes is crucial for not only local defense in the intestine but also proper systemic immune responses. Although intestinal epithelial cells (IECs) play important roles in cytokine-mediated...
14.
Kurematsu C, Sawada M, Ohmuraya M, Tanaka M, Kuboyama K, Ogino T, et al.
J Exp Med . 2022 Mar; 219(4). PMID: 35297954
New neurons, continuously added in the adult olfactory bulb (OB) and hippocampus, are involved in information processing in neural circuits. Here, we show that synaptic pruning of adult-born neurons by...
15.
Nishiura H, Imasaka M, Yamanegi K, Fujimoto J, Ohmuraya M
Front Physiol . 2022 Jan; 12:795508. PMID: 35058804
Almost all mature cells that undergo apoptosis in an age-dependent or an accidental manner are completely recovered in tissue-specific microenvironments without any physiological changes. After peripheral blood leukocytes are released...
16.
Saiki Y, Jiang C, Ohmuraya M, Furukawa T
Cancers (Basel) . 2022 Jan; 14(1). PMID: 35008235
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy, and the seventh leading cause of cancer-related deaths worldwide. An improved understanding of tumor biology and novel therapeutic discoveries are needed...
17.
Yoshikawa Y, Yamada Y, Emi M, Atanesyan L, Smout J, de Groot K, et al.
Cancer Sci . 2021 Oct; 113(1):297-307. PMID: 34687579
Precise quantification of copy-number alterations (CNAs) in a tumor genome is difficult. We have applied a comprehensive copy-number analysis method, digital multiplex ligation-dependent probe amplification (digitalMLPA), for targeted gene copy-number...
18.
Mareninova O, Dillon D, Wightman C, Yakubov I, Takahashi T, Gaisano H, et al.
Cell Mol Gastroenterol Hepatol . 2021 Oct; 13(2):599-622. PMID: 34610499
Background: Autophagosome, the central organelle in autophagy process, can assemble via canonical pathway mediated by LC3-II, the lipidated form of autophagy-related protein LC3/ATG8, or noncanonical pathway mediated by the small...
19.
Iijima A, Kanemaru K, Wang Y, Nabekura T, Nakamura Y, Fujisawa Y, et al.
Biochem Biophys Res Commun . 2021 Jul; 568:193-194. PMID: 34246465
No abstract available.
20.
Iijima A, Kanemaru K, Wang Y, Nabekura T, Nakamura Y, Fujisawa Y, et al.
Biochem Biophys Res Commun . 2021 May; 561:101-105. PMID: 34020140
Mast cells (MCs) are present in various organs including the skin, peritoneal cavity, lung, and intestine and involved in the development of allergic diseases and host defense against infection. However,...