Masaki Ohmuraya
Overview
Explore the profile of Masaki Ohmuraya including associated specialties, affiliations and a list of published articles.
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Articles
89
Citations
5592
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Recent Articles
1.
Hamada K, Nakanishi Y, Muta Y, Omatsu M, Iwane K, Ikeda M, et al.
Cell Mol Gastroenterol Hepatol
. 2024 Dec;
19(3):101435.
PMID: 39631567
Background & Aims: Retinoblastoma-binding protein 9 (RBBP9) was initially reported as cell cycle regulator via RB/E2F. Accumulating evidence has revealed the importance of RBBP9 in physiological and pathological states including...
2.
Tokuhara Y, Ukon S, Watanabe S, Tatsumi Y, Yoshikawa H, Ohmuraya M, et al.
Exp Anim
. 2024 Nov;
PMID: 39537175
Gracile axonal dystrophy (gad) mutant mice present with autosomal recessive inherited sensory ataxia in the early stages, followed by age-dependent motor ataxia. This phenotype is caused by a mutation in...
3.
Tsuchiya Y, Seki T, Kobayashi K, Komazawa-Sakon S, Shichino S, Nishina T, et al.
Nat Commun
. 2023 Oct;
14(1):6304.
PMID: 37813881
Liver fibrosis results from chronic liver injury triggered by factors such as viral infection, excess alcohol intake, and lipid accumulation. However, the mechanisms underlying liver fibrosis are not fully understood....
4.
Mehanna S, Arakawa S, Imasaka M, Chen W, Nakanishi Y, Nishiura H, et al.
Dev Biol
. 2023 Sep;
504:113-119.
PMID: 37739117
Beclin1 (Becn1) is a multifunctional protein involved in autophagy regulation, membrane trafficking, and tumor suppression. In this study, we examined the roles of Becn1 in the pancreas development by generating...
5.
Chen W, Imasaka M, Lee M, Fukui H, Nishiura H, Ohmuraya M
Sci Rep
. 2023 Jul;
13(1):12201.
PMID: 37500741
Chronic pancreatitis (CP) is a disease characterized by the inflammation and destruction of pancreatic tissue, leading to the replacement of functional tissue with fibrotic tissue. The regenerating gene (Reg) family...
6.
Tada A, Minami T, Kitai H, Higashiguchi Y, Tokuda M, Higashiyama T, et al.
Lung Cancer
. 2023 May;
180:107219.
PMID: 37146474
Malignant pleural mesothelioma (MPM) is an asbestos-related fatal malignant neoplasm. Although there has been no reliable chemotherapeutic regimen other than combination therapy of cisplatin and pemetrexed for two decades, combination...
7.
Tsujioka M, Miyazawa K, Ohmuraya M, Nibe Y, Shirokawa T, Hayasaka H, et al.
Cell Death Dis
. 2023 Apr;
14(4):256.
PMID: 37031228
Numerous studies have investigated the various cellular responses against genotoxic stress, including those mediated by focal adhesions. We here identified a novel type of focal adhesion remodelling that occurs under...
8.
Horii Y, Matsuda S, Toyota C, Morinaga T, Nakaya T, Tsuchiya S, et al.
Nat Commun
. 2023 Feb;
14(1):550.
PMID: 36754961
Myofibroblasts cause tissue fibrosis by producing extracellular matrix proteins, such as collagens. Humoral factors like TGF-β, and matrix stiffness are important for collagen production by myofibroblasts. However, the molecular mechanisms...
9.
Murai S, Takakura K, Sumiyama K, Moriwaki K, Terai K, Komazawa-Sakon S, et al.
Commun Biol
. 2022 Dec;
5(1):1331.
PMID: 36471162
Necroptosis is a regulated form of cell death involved in various pathological conditions, including ischemic reperfusion injuries, virus infections, and drug-induced tissue injuries. However, it is not fully understood when...
10.
Takagi-Kimura M, Tada A, Kijima T, Kubo S, Ohmuraya M, Yoshikawa Y
Genes Cells
. 2022 Oct;
27(12):731-740.
PMID: 36300836
BRCA1 associated protein 1 (BAP1) is a ubiquitin C-terminal hydrolase that deubiquitinates histone H2AK119ub and other proteins and regulates the expression of multiple genes. The knockout of this tumor suppressor...