Maryam Pourmaleki
Overview
Explore the profile of Maryam Pourmaleki including associated specialties, affiliations and a list of published articles.
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8
Citations
492
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0
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Recent Articles
1.
Pourmaleki M, Jones C, Mellinghoff S, Greenstein B, Kumar P, Foronda M, et al.
Clin Cancer Res
. 2024 Jul;
30(17):3881-3893.
PMID: 38949890
Purpose: Classic Hodgkin lymphoma (cHL) is a B-cell lymphoma that occurs primarily in young adults and, less frequently, in elderly individuals. A hallmark of cHL is the exceptional scarcity (1%-5%)...
2.
Pourmaleki M, Socci N, Hollmann T, Mellinghoff I
Cancer Discov
. 2023 Apr;
13(4):824-828.
PMID: 37009699
The shift in cancer therapy from broadly cytotoxic agents toward "personalized" treatments that target specific alterations in each patient's tumor requires diagnostic pathology approaches that are quantitative and biospecimen-friendly. Novel...
3.
Vazquez-Garcia I, Uhlitz F, Ceglia N, Lim J, Wu M, Mohibullah N, et al.
Nature
. 2022 Dec;
612(7941):778-786.
PMID: 36517593
High-grade serous ovarian cancer (HGSOC) is an archetypal cancer of genomic instability patterned by distinct mutational processes, tumour heterogeneity and intraperitoneal spread. Immunotherapies have had limited efficacy in HGSOC, highlighting...
4.
Pourmaleki M, Jones C, Ariyan C, Zeng Z, Pirun M, Navarrete D, et al.
Cancer Immunol Res
. 2022 Jan;
10(3):303-313.
PMID: 35013003
Cancer immunotherapy can result in lasting tumor regression, but predictive biomarkers of treatment response remain ill-defined. Here, we performed single-cell proteomics, transcriptomics, and genomics on matched untreated and IL2 injected...
5.
Pourmaleki M, Young J, Socci N, Chiang S, Edelweiss M, Li Y, et al.
Oncotarget
. 2019 Nov;
10(58):6152-6167.
PMID: 31692889
Extramammary Paget disease (EMPD) is a rare cutaneous adenocarcinoma of the anogenital region most commonly treated with surgical excision. Surgical margin clearance is often problematic and recurrence rates remain high...
6.
Jonsson P, Lin A, Young R, DiStefano N, Hyman D, Li B, et al.
Clin Cancer Res
. 2019 Jul;
25(18):5537-5547.
PMID: 31263031
Purpose: The genomic landscape of gliomas has been characterized and now contributes to disease classification, yet the relationship between molecular profile and disease progression and treatment response remain poorly understood....
7.
Miller A, Shah R, Pentsova E, Pourmaleki M, Briggs S, DiStefano N, et al.
Nature
. 2019 Jan;
565(7741):654-658.
PMID: 30675060
Diffuse gliomas are the most common malignant brain tumours in adults and include glioblastomas and World Health Organization (WHO) grade II and grade III tumours (sometimes referred to as lower-grade...
8.
Oldrini B, Hsieh W, Erdjument-Bromage H, Codega P, Carro M, Curiel-Garcia A, et al.
Nat Commun
. 2017 Dec;
8(1):2035.
PMID: 29229958
Transport of macromolecules through the nuclear pore by importins and exportins plays a critical role in the spatial regulation of protein activity. How cancer cells co-opt this process to promote...