Mary R Hutson
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Explore the profile of Mary R Hutson including associated specialties, affiliations and a list of published articles.
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14
Citations
704
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Recent Articles
1.
Hutson M, Keyte A, Hernandez-Morales M, Gibbs E, Kupchinsky Z, Argyridis I, et al.
Sci Signal
. 2017 Oct;
10(500).
PMID: 29018170
Birth defects of the heart and face are common, and most have no known genetic cause, suggesting a role for environmental factors. Maternal fever during the first trimester is an...
2.
Andersen N, Ramachandran K, Bao M, Kirby M, Pitt G, Hutson M
J Mol Cell Cardiol
. 2014 Dec;
80:1-9.
PMID: 25536179
In utero interventions aimed at restoring left ventricular hemodynamic forces in fetuses with prenatally diagnosed hypoplastic left heart syndrome failed to stimulate ventricular myocardial growth during gestation, suggesting chamber growth...
3.
Sinha T, Li D, Theveniau-Ruissy M, Hutson M, Kelly R, Wang J
Hum Mol Genet
. 2014 Nov;
24(6):1704-16.
PMID: 25410658
Outflow tract (OFT) malformation accounts for ∼30% of human congenital heart defects and manifests frequently in TBX1 haplo-insufficiency associated DiGeorge (22q11.2 deletion) syndrome. OFT myocardium originates from second heart field...
4.
Evolutionary and developmental origins of the cardiac neural crest: building a divided outflow tract
Keyte A, Alonzo-Johnsen M, Hutson M
Birth Defects Res C Embryo Today
. 2014 Sep;
102(3):309-23.
PMID: 25227322
The cardiac neural crest cells (CNCCs) have played an important role in the evolution and development of the vertebrate cardiovascular system: from reinforcement of the developing aortic arch arteries early...
5.
Leddy H, McNulty A, Lee S, Rothfusz N, Gloss B, Kirby M, et al.
FASEB J
. 2014 Mar;
28(6):2525-37.
PMID: 24577120
Point mutations in the calcium-permeable TRPV4 ion channel have been identified as the cause of autosomal-dominant human motor neuropathies, arthropathies, and skeletal malformations of varying severity. The objective of this...
6.
Sato A, Scholl A, Kuhn E, Kuhn E, Stadt H, Decker J, et al.
Dev Biol
. 2011 Mar;
354(1):18-30.
PMID: 21419761
Cardiac neural crest cells migrate into the pharyngeal arches where they support development of the pharyngeal arch arteries. The pharyngeal endoderm and ectoderm both express high levels of FGF8. We...
7.
Dyer L, Makadia F, Scott A, Pegram K, Hutson M, Kirby M
Dev Biol
. 2010 Oct;
348(2):167-76.
PMID: 20920499
Sonic hedgehog signaling in the secondary heart field has a clear role in cardiac arterial pole development. In the absence of hedgehog signaling, proliferation is reduced in secondary heart field...
8.
Kirby M, Hutson M
Cell Adh Migr
. 2010 Oct;
4(4):609-21.
PMID: 20890117
Cardiac neural crest cells originate as part of the postotic caudal rhombencephalic neural crest stream. Ectomesenchymal cells in this stream migrate to the circumpharyngeal ridge and then into the caudal...
9.
van den Berg G, Abu-Issa R, de Boer B, Hutson M, de Boer P, Soufan A, et al.
Circ Res
. 2008 Dec;
104(2):179-88.
PMID: 19059840
Recent studies have shown that the primary heart tube continues to grow by addition of cells from the coelomic wall. This growth occurs concomitantly with embryonic folding and formation of...
10.
Hutson M, Kirby M
Semin Cell Dev Biol
. 2007 Jan;
18(1):101-10.
PMID: 17224285
Neural crest cells are multipotential cells that delaminate from the dorsal neural tube and migrate widely throughout the body. A subregion of the cranial neural crest originating between the otocyst...