Mary N Latimer
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Explore the profile of Mary N Latimer including associated specialties, affiliations and a list of published articles.
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12
Citations
143
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Recent Articles
1.
Latimer M, Williams L, Shanmugan G, Carpenter B, Lazar M, Dierickx P, et al.
Commun Biol
. 2023 Nov;
6(1):1149.
PMID: 37952007
Circadian disruption increases cardiovascular disease (CVD) risk, through poorly understood mechanisms. Given that small RNA species are critical modulators of cardiac physiology/pathology, we sought to determine the extent to which...
2.
Mia S, Sonkar R, Williams L, Latimer M, Rawnsley D, Rana S, et al.
JACC Basic Transl Sci
. 2023 Oct;
8(9):1141-1156.
PMID: 37791313
Circadian clocks temporally orchestrate biological processes critical for cellular/organ function. For example, the cardiomyocyte circadian clock modulates cardiac metabolism, signaling, and electrophysiology over the course of the day, such that,...
3.
Mihaylova M, Chaix A, Delibegovic M, Ramsey J, Bass J, Melkani G, et al.
Cell Metab
. 2023 Jul;
35(7):1114-1131.
PMID: 37392742
An epidemic of obesity has affected large portions of the world, increasing the risk of developing many different age-associated diseases, including cancer, cardiovascular disease, and diabetes. In contrast with the...
4.
Alsharif H, Latimer M, Perez K, Alexander J, Rahman M, Challa A, et al.
Metabolites
. 2023 Jun;
13(6).
PMID: 37367869
Effective energy expenditure is critical for maintaining body weight (BW). However, underlying mechanisms contributing to increased BW remain unknown. We characterized the role of brain angiogenesis inhibitor-3 (BAI3/ADGRB3), an adhesion...
5.
Latimer M, Young M
Cells
. 2022 May;
11(9).
PMID: 35563800
The cardiomyocyte circadian clock temporally governs fundamental cellular processes, leading to 24-h rhythms in cardiac properties (such as electrophysiology and contractility). The importance of this cell-autonomous clock is underscored by...
6.
Sonkar R, Berry R, Latimer M, Prabhu S, Young M, Frank S
Front Pharmacol
. 2022 Mar;
13:836725.
PMID: 35250583
Circadian clocks regulate numerous biological processes, at whole body, organ, and cellular levels. This includes both hormone secretion and target tissue sensitivity. Although growth hormone (GH) secretion is time-of-day-dependent (increased...
7.
Young M, Latimer M
Chronobiol Int
. 2021 Jun;
40(1):13-26.
PMID: 34162286
Numerous aspects of cardiovascular physiology (e.g., heart rate, blood pressure) and pathology (e.g., myocardial infarction and sudden cardiac death) exhibit time-of-day-dependency. In association with day-night differences in energetic demand and...
8.
Latimer M, Sonkar R, Mia S, Frayne I, Carter K, Johnson C, et al.
J Mol Cell Cardiol
. 2021 Apr;
157:31-44.
PMID: 33894212
Essentially all biological processes fluctuate over the course of the day, manifesting as time-of-day-dependent variations with regards to the way in which organ systems respond to normal behaviors. For example,...
9.
Mia S, Sonkar R, Williams L, Latimer M, Frayne Robillard I, Diwan A, et al.
FASEB J
. 2021 Mar;
35(3):e21298.
PMID: 33660366
An intrinsic property of the heart is an ability to rapidly and coordinately adjust flux through metabolic pathways in response to physiologic stimuli (termed metabolic flexibility). Cardiac metabolism also fluctuates...
10.
Mia S, Kane M, Latimer M, Reitz C, Sonkar R, Benavides G, et al.
Am J Physiol Heart Circ Physiol
. 2020 May;
318(6):H1487-H1508.
PMID: 32357113
Cell-autonomous circadian clocks have emerged as temporal orchestrators of numerous biological processes. For example, the cardiomyocyte circadian clock modulates transcription, translation, posttranslational modifications, ion homeostasis, signaling cascades, metabolism, and contractility...