Mary E Pownall
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Explore the profile of Mary E Pownall including associated specialties, affiliations and a list of published articles.
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20
Citations
285
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Recent Articles
1.
White L, Russell A, Pizzey A, Dasmahapatra K, Pownall M
J Dev Biol
. 2023 May;
11(2).
PMID: 37218813
The gene was duplicated during the teleost whole genome duplication and, while a second gene () was subsequently lost from the genomes of some lineages (including zebrafish), many fish lineages...
2.
White L, Rose M, Lawson M, Joyce D, Smith A, Thomas G, et al.
Biol Open
. 2022 Oct;
11(11).
PMID: 36250323
Most fish excrete their nitrogenous waste across the gills as ammonia through the activity of the Rhesus glycoprotein ammonium transporters. In contrast, fish of the subgenus Alcolapia (Oreochromis) are the...
3.
White L, Sutton G, Shechonge A, Day J, Dasmahapatra K, Pownall M
R Soc Open Sci
. 2020 Nov;
7(10):201200.
PMID: 33204476
Tetrapods and fish have adapted distinct carbamoyl-phosphate synthase (CPS) enzymes to initiate the ornithine urea cycle during the detoxification of nitrogenous wastes. We report evidence that in the ureotelic subgenus...
4.
Sutton G, White L, Ford A, Shechonge A, Day J, Dasmahapatra K, et al.
J Dev Biol
. 2020 Oct;
8(4).
PMID: 33020460
Although it is widely accepted that the cellular and molecular mechanisms of vertebrate cardiac development are evolutionarily conserved, this is on the basis of data from only a few model...
5.
Elsy M, Rowbotham A, Lord H, Isaacs H, Pownall M
Int J Dev Biol
. 2020 Mar;
63(11-12):631-639.
PMID: 32149373
Fibroblast growth factors (FGFs) comprise a family of signalling molecules with essential roles in early embryonic development across animal species. The role of FGFs in mesoderm formation and patterning in...
6.
McQueen C, Hughes G, Pownall M
Dev Biol
. 2019 Jun;
454(1):74-84.
PMID: 31173763
Gene regulatory networks underpinning skeletal muscle determination and differentiation have been extensively investigated, providing molecular insights into how cell lineages are established during development. These studies have exclusively focused on...
7.
Jokl E, Hughes G, Cracknell T, Pownall M, Blanco G
Dis Model Mech
. 2018 Jun;
11(7).
PMID: 29914939
The importance of kyphoscoliosis peptidase (KY) in skeletal muscle physiology has recently been emphasised by the identification of novel human myopathies associated with KY deficiency. Neither the pathogenic mechanism of...
8.
Ramsbottom S, Pownall M
J Dev Biol
. 2016 Aug;
4(3):23.
PMID: 27547735
The hedgehog (Hh) signalling pathway is conserved throughout metazoans and plays an important regulatory role in both embryonic development and adult homeostasis. Many levels of regulation exist that control the...
9.
Fellgett S, Ramsbottom S, Maguire R, Cross S, OToole P, Pownall M
J Vis Exp
. 2015 Dec;
(106):e53162.
PMID: 26709854
This protocol describes a method to visualise ligands distributed across a field of cells. The ease of expressing exogenous proteins, together with the large size of their cells in early...
10.
Cook D, Fellgett S, Pownall M, OShea P, Genever P
Stem Cell Res
. 2014 Jan;
12(2):415-27.
PMID: 24382458
Bone marrow stromal cells (BMSCs, also known as bone marrow-derived mesenchymal stem cells) can differentiate into multiple lineages including osteogenic and adipogenic cells. Wnt signalling has been implicated in controlling...