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Martina Turroja

Explore the profile of Martina Turroja including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 3018
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Recent Articles
1.
Wang Z, Muecksch F, Raspe R, Johannsen F, Turroja M, Canis M, et al.
J Exp Med . 2023 Jun; 220(9). PMID: 37368240
Despite mRNA vaccination, elderly individuals remain especially vulnerable to severe consequences of SARS-CoV-2 infection. Here, we compare the memory B cell responses in a cohort of elderly and younger individuals...
2.
Schaefer-Babajew D, Wang Z, Muecksch F, Cho A, Loewe M, Cipolla M, et al.
Nature . 2022 Dec; 613(7945):735-742. PMID: 36473496
Feedback inhibition of humoral immunity by antibodies was first documented in 1909. Subsequent studies showed that, depending on the context, antibodies can enhance or inhibit immune responses. However, little is...
3.
Wang Z, Zhou P, Muecksch F, Cho A, Ben Tanfous T, Canis M, et al.
J Exp Med . 2022 Sep; 219(12). PMID: 36149398
Individuals who receive a third mRNA vaccine dose show enhanced protection against severe COVID-19, but little is known about the impact of breakthrough infections on memory responses. Here, we examine...
4.
Wang Z, Muecksch F, Muenn F, Cho A, Zong S, Raspe R, et al.
J Exp Med . 2022 Aug; 219(10). PMID: 36006380
The SARS-CoV-2 pandemic prompted a global vaccination effort and the development of numerous COVID-19 vaccines at an unprecedented scale and pace. As a result, current COVID-19 vaccination regimens comprise diverse...
5.
Schaefer-Babajew D, Wang Z, Muecksch F, Cho A, Raspe R, Johnson B, et al.
medRxiv . 2022 Aug; PMID: 35982682
Feedback inhibition of humoral immunity by antibodies was initially documented in guinea pigs by Theobald Smith in 1909, who showed that passive administration of excess anti-Diphtheria toxin inhibited immune responses....
6.
Gaebler C, DaSilva J, Bednarski E, Muecksch F, Schmidt F, Weisblum Y, et al.
Open Forum Infect Dis . 2022 Jul; 9(7):ofac227. PMID: 35818364
The emergence of severe acute respiratory syndrome coronavirus 2 variants that have greater transmissibility and resistance to neutralizing antibodies has increased the incidence of breakthrough infections. We show that breakthrough...
7.
Cho A, Muecksch F, Wang Z, Ben Tanfous T, DaSilva J, Raspe R, et al.
J Exp Med . 2022 Jul; 219(8). PMID: 35776090
The single-dose Ad.26.COV.2 (Janssen) vaccine elicits lower levels of neutralizing antibodies and shows more limited efficacy in protection against infection than either of the two available mRNA vaccines. In addition,...
8.
Wang Z, Muecksch F, Cho A, Gaebler C, Hoffmann H, Ramos V, et al.
Immunity . 2022 Apr; 55(6):998-1012.e8. PMID: 35447092
SARS-CoV-2 infection or vaccination produces neutralizing antibody responses that contribute to better clinical outcomes. The receptor-binding domain (RBD) and the N-terminal domain (NTD) of the spike trimer (S) constitute the...
9.
Muecksch F, Wang Z, Cho A, Gaebler C, Ben Tanfous T, DaSilva J, et al.
Nature . 2022 Apr; 607(7917):128-134. PMID: 35447027
The Omicron variant of SARS-CoV-2 infected many vaccinated and convalescent individuals. Despite the reduced protection from infection, individuals who received three doses of an mRNA vaccine were highly protected from...
10.
Gaebler C, Nogueira L, Stoffel E, Oliveira T, Breton G, Millard K, et al.
Nature . 2022 Apr; 606(7913):368-374. PMID: 35418681
HIV-1 infection remains a public health problem with no cure. Anti-retroviral therapy (ART) is effective but requires lifelong drug administration owing to a stable reservoir of latent proviruses integrated into...