Martin Pruschy
Overview
Explore the profile of Martin Pruschy including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
74
Citations
1270
Followers
0
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Beckers C, Vasilikos L, Moor L, Pruschy M
Clin Transl Radiat Oncol
. 2025 Feb;
51:100920.
PMID: 39898333
3D spheroids are a valuable tool for investigating the interplay between hypoxia and radioresistance. However, standardized methods for visualizing normoxic and hypoxic regions within spheroids and assessing treatment responses are...
2.
Kirschner M, Meerang M, Orlowski V, Furrer K, Tschanz F, Grgic I, et al.
JTCVS Open
. 2025 Jan;
22():491-503.
PMID: 39780777
Objective: To test the safety and efficacy of combination treatment for pleural mesothelioma (PM) with intracavitary cisplatin-fibrin (cis-fib) plus hemithoracic irradiation (IR) applied after lung-sparing surgery in an orthotopic immunocompetent...
3.
Rondeau J, Lipari S, Mathieu B, Beckers C, Van de Velde J, Mignion L, et al.
Cell Death Discov
. 2024 Dec;
10(1):514.
PMID: 39730333
Hypoxic tumors are radioresistant stemming from the fact that oxygen promotes reactive oxygen species (ROS) propagation after water radiolysis and stabilizes irradiation-induced DNA damage. Therefore, an attractive strategy to radiosensitize...
4.
Catalytically Active Ti-Based Nanomaterials for Hydroxyl Radical Mediated Clinical X-Ray Enhancement
Gerken L, Beckers C, Brugger B, Kissling V, Gogos A, Wee S, et al.
Adv Sci (Weinh)
. 2024 Nov;
11(47):e2406198.
PMID: 39501581
Nanoparticle radioenhancement offers a promising strategy for augmenting radiotherapy by locally increasing radiation damage to tumor tissue. While past research has predominantly focused on nanomaterials with high atomic numbers, such...
5.
Telarovic I, Yong C, Kurz L, Vetrugno I, Reichl S, Fernandez A, et al.
Nat Commun
. 2024 Jul;
15(1):5500.
PMID: 38951172
Cancer resistance to immune checkpoint inhibitors motivated investigations into leveraging the immunostimulatory properties of radiotherapy to overcome immune evasion and to improve treatment response. However, clinical benefits of radiotherapy-immunotherapy combinations...
6.
Sharma A, Pruschy M
Prog Tumor Res
. 2024 Jan;
44:25-40.
PMID: 38243414
The tumor microenvironment comprises multiple different cell types and structural and functional components, and defines a unique tumor milieu on the individual tumor level. Several biological processes in the microenvironment...
7.
Beckers C, Pruschy M, Vetrugno I
Semin Cancer Biol
. 2023 Dec;
98:19-30.
PMID: 38040401
Hypoxia in solid tumors is an important predictor of poor clinical outcome to radiotherapy. Both physicochemical and biological processes contribute to a reduced sensitivity of hypoxic tumor cells to ionizing...
8.
Beckers C, Vasilikos L, Fernandez A, Moor L, Pruschy M
Radiother Oncol
. 2023 Dec;
190:110039.
PMID: 38040123
Background: Cancer cell survival under stress conditions is a prerequisite for the development of treatment resistance. The survival kinase DYRK1B is a key regulator of stress survival pathways and might...
9.
Gerken L, Gerdes M, Pruschy M, Herrmann I
Mater Horiz
. 2023 Aug;
10(10):4059-4082.
PMID: 37555747
Radiotherapy is a key pillar of solid cancer treatment. Despite a high level of conformal dose deposition, radiotherapy is limited due to co-irradiation of organs at risk and subsequent normal...
10.
Waller V, Tschanz F, Winkler R, Pruschy M
Front Oncol
. 2023 Mar;
13:1117326.
PMID: 36998455
Purpose: Ionizing radiation (IR) enhances the migratory capacity of cancer cells. Here we investigate in non-small-cell-lung-cancer (NSCLC) cells a novel link between IR-enhanced ADAM17 activity and the non-canonical pathway of...