Michael A Grotzer
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Explore the profile of Michael A Grotzer including associated specialties, affiliations and a list of published articles.
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88
Citations
1545
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Recent Articles
1.
Gries A, Santhana Kumar K, Kuttler F, Ozalp O, Akle V, Zhang H, et al.
Neoplasia
. 2024 Nov;
59:101078.
PMID: 39514961
The impact of the tissue context on tumor growth and drug response in medulloblastoma (MB) is poorly understood. To gain insights into the growth and dissemination behavior of the MB...
2.
Weiser A, Hengartner H, Kottke R, Grehten P, Toelle S, Gerber N, et al.
J Pediatr Hematol Oncol
. 2023 Feb;
45(4):e543-e546.
PMID: 36730977
Diencephalic syndrome is usually associated with tumors in the hypothalamic region, rarely occurring in patients with neurofibromatosis type 1 (NF1)-associated gliomas. We describe the clinical presentation and response to treatment...
3.
Migliavacca J, Zullig B, Capdeville C, Grotzer M, Baumgartner M
Commun Biol
. 2022 Aug;
5(1):880.
PMID: 36028581
No abstract available.
4.
Migliavacca J, Zullig B, Capdeville C, Grotzer M, Baumgartner M
Commun Biol
. 2022 Aug;
5(1):795.
PMID: 35941177
MAP4K4 is associated with increased motility and reduced proliferation in tumor cells, but the regulation of this dichotomous functionality remained elusive. We find that MAP4K4 interacts with striatin 3 and...
5.
Boller D, Doepfner K, Laurentiis A, Guerreiro A, Marinov M, Shalaby T, et al.
Anticancer Res
. 2022 May;
42(6):3217-3230.
PMID: 35641277
Background: Eight human catalytic phosphoinositide 3-kinase (PI3K) isoforms exist which are subdivided into three classes. While class I isoforms have been well-studied in cancer, little is known about the functions...
6.
Capdeville C, Russo L, Penton D, Migliavacca J, Zecevic M, Gries A, et al.
Life Sci Alliance
. 2022 Mar;
5(6).
PMID: 35296518
The composition of the plasma membrane (PM)-associated proteome of tumor cells determines cell-cell and cell-matrix interactions and the response to environmental cues. Whether the PM-associated proteome impacts the phenotype of...
7.
Metzger S, Weiser A, Gerber N, Otth M, Scheinemann K, Krayenbuhl N, et al.
J Neurooncol
. 2022 Feb;
157(2):319.
PMID: 35226242
No abstract available.
8.
Przystal J, Cosentino C, Yadavilli S, Zhang J, Laternser S, Bonner E, et al.
Neuro Oncol
. 2022 Feb;
24(9):1438-1451.
PMID: 35157764
Background: Pediatric diffuse midline gliomas (DMGs) are incurable childhood cancers. The imipridone ONC201 has shown early clinical efficacy in a subset of DMGs. However, the anticancer mechanisms of ONC201 and...
9.
Metzger S, Weiser A, Gerber N, Otth M, Scheinemann K, Krayenbuhl N, et al.
J Neurooncol
. 2022 Feb;
157(2):307-317.
PMID: 35147892
Purpose: The challenges of treating central nervous system (CNS) tumors in young children are many. These include age-specific tumor characteristics, limited treatment options, and susceptibility of the developing CNS to...
10.
Bonner E, Waszak S, Grotzer M, Mueller S, Nazarian J
Neuro Oncol
. 2020 Dec;
23(4):542-556.
PMID: 33336683
ONC201 is the first member of the imipridone family of anticancer drugs to enter the clinic for the treatment of diverse solid and hematologic cancers. A subset of pediatric and...