Martin Marsala
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Explore the profile of Martin Marsala including associated specialties, affiliations and a list of published articles.
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110
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4427
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Recent Articles
1.
Martin J, Cleary D, Abraham M, Mendoza M, Cabrera B, Jamieson C, et al.
Cell Rep Med
. 2024 Dec;
5(12):101841.
PMID: 39626671
We report the long-term results for a phase 1 study of neural stem cell transplantation for chronic spinal cord injury. The trial was registered on ClinicalTrials.gov as NCT01772810. The primary...
2.
Lopez-Erauskin J, Bravo-Hernandez M, Presa M, Baughn M, Melamed Z, Beccari M, et al.
Nat Neurosci
. 2023 Nov;
27(1):34-47.
PMID: 37996528
The mRNA transcript of the human STMN2 gene, encoding for stathmin-2 protein (also called SCG10), is profoundly impacted by TAR DNA-binding protein 43 (TDP-43) loss of function. The latter is...
3.
Kobayashi Y, Shigyo M, Platoshyn O, Marsala S, Kato Jr T, Takamura N, et al.
Cell Transplant
. 2023 Apr;
32:9636897221107009.
PMID: 37088987
One of the challenges in clinical translation of cell-replacement therapies is the definition of optimal cell generation and storage/recovery protocols which would permit a rapid preparation of cell-treatment products for...
4.
Shigyo M, Kobayashi Y, Platoshyn O, Marsala S, Kato Jr T, Takamura N, et al.
Cell Transplant
. 2023 Mar;
32:9636897231163232.
PMID: 36959733
The critical requirements in developing clinical-grade human-induced pluripotent stem cells-derived neural precursors (hiPSCs-NPCs) are defined by expandability, genetic stability, predictable post-grafting differentiation, and acceptable safety profile. Here, we report on...
5.
Wang S, Ichinomiya T, Savchenko P, Wang D, Sawada A, Li X, et al.
Theranostics
. 2022 Aug;
12(12):5389-5403.
PMID: 35910808
Elevating neuroprotective proteins using adeno-associated virus (AAV)-mediated gene delivery shows great promise in combating devastating neurodegenerative diseases. Amyotrophic lateral sclerosis (ALS) is one such disease resulting from loss of upper...
6.
Tadokoro T, Bravo-Hernandez M, Agashkov K, Kobayashi Y, Platoshyn O, Navarro M, et al.
Mol Ther
. 2022 May;
30(8):2722-2745.
PMID: 35524407
Second-order spinal cord excitatory neurons play a key role in spinal processing and transmission of pain signals to the brain. Exogenously induced change in developmentally imprinted excitatory neurotransmitter phenotypes of...
7.
Miki S, Koga T, McKinney A, Parisian A, Tadokoro T, Vadla R, et al.
Neuro Oncol
. 2022 Mar;
24(12):2063-2075.
PMID: 35325218
Background: Heterozygous TERT (telomerase reverse transcriptase) promoter mutations (TPMs) facilitate TERT expression and are the most frequent mutation in glioblastoma (GBM). A recent analysis revealed this mutation is one of...
8.
Sucha R, Kubickova M, cervenka J, Hruska-Plochan M, Bohaciakova D, Kepkova K, et al.
Biol Open
. 2021 Aug;
10(8).
PMID: 34357391
Human multipotent neural stem cells could effectively be used for the treatment of a variety of neurological disorders. However, a defining signature of neural stem cell lines that would be...
9.
Batra R, Nelles D, Roth D, Krach F, Nutter C, Tadokoro T, et al.
Nat Biomed Eng
. 2020 Sep;
5(2):157-168.
PMID: 32929188
Myotonic dystrophy type I (DM1) is a multisystemic autosomal-dominant inherited human disorder that is caused by CTG microsatellite repeat expansions (MREs) in the 3' untranslated region of DMPK. Toxic RNAs...
10.
Lukacova N, Hricova L, Kisucka A, Papcunova S, Bimbova K, Bacova M, et al.
Front Physiol
. 2020 Jul;
11:700.
PMID: 32655417
We previously reported NO/sGC signaling in the upper respiratory pathway, receiving input from the respiratory neurons of the brainstem to phrenic motoneurons in the C3-C6 spinal cord. In order to...