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Martin Eefsen

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Citations 480
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Recent Articles
1.
Larsen F, Schmidt L, Bernsmeier C, Rasmussen A, Isoniemi H, Patel V, et al.
J Hepatol . 2015 Sep; 64(1):69-78. PMID: 26325537
Background & Aims: Acute liver failure (ALF) often results in cardiovascular instability, renal failure, brain oedema and death either due to irreversible shock, cerebral herniation or development of multiple organ...
2.
Larsen R, Kjaer M, Eefsen M, Larsen F, Bjerring P
World J Hepatol . 2013 Sep; 5(9):513-20. PMID: 24073303
Aim: To investigate the neuroprotective potential of ciclosporin during acute liver failure. We evaluated the effect of intrathecally administered ciclosporin on intracranial pressure, brain water content and aquaporin-4 expression in...
3.
Banares R, Nevens F, Larsen F, Jalan R, Albillos A, Dollinger M, et al.
Hepatology . 2012 Dec; 57(3):1153-62. PMID: 23213075
Unlabelled: Acute-on-chronic liver failure (ACLF) is a frequent cause of death in cirrhosis. Albumin dialysis with the molecular adsorbent recirculating system (MARS) decreases retained substances and improves hemodynamics and hepatic...
4.
Buchard A, Eefsen M, Semb S, Andersen S, Morling N, Bendtsen F, et al.
Clin Toxicol (Phila) . 2011 Dec; 50(1):27-33. PMID: 22175791
The aim of this study was to assess if genetic variants in the glutathione-S-transferase genes GST-T1, M1, and P1 reflect risk factors in acetaminophen (APAP)-poisoned patients assessed by investigation of...
5.
Bjerring P, Eefsen M, Larsen F, Bernal W, Wendon J
Hepatology . 2011 Mar; 53(6):1986-94. PMID: 21384403
Unlabelled: Intravenous infusion of magnesium sulfate prevents seizures in patients with eclampsia and brain edema after traumatic brain injury. Neuroprotection is achieved by controlling cerebral blood flow (CBF), intracranial pressure,...
6.
Eefsen M, Jelnes P, Schmidt L, Vainer B, Bisgaard H, Larsen F
Metab Brain Dis . 2010 Oct; 25(3):315-23. PMID: 20938728
Cerebral edema is a feared complication to acute liver failure (ALF), but the pathogenesis is still poorly understood. The water channels Aquaporin-1 (Aqp1) and -4 (Aqp4) has been associated with...
7.
Bjerring P, Eefsen M, Hansen B, Larsen F
Metab Brain Dis . 2008 Dec; 24(1):5-14. PMID: 19050999
Acute liver failure (ALF) is a condition with an unfavourable prognosis. Multiorgan failure and circulatory collapse are frequent causes of death, but cerebral edema and intracranial hypertension (ICH) are also...
8.
Eefsen M, Dethloff T, Frederiksen H, Hauerberg J, Hansen B, Larsen F
J Hepatol . 2007 Jun; 47(3):381-6. PMID: 17599633
Background/aims: Volume expansion and inotropic support with catecholamines are sometimes insufficient to ensure adequate blood pressure and cerebral perfusion in acute liver failure (ALF). The aim of this study was...
9.
Larsen F, Vainer B, Eefsen M, Bjerring P, Hansen B
World J Gastroenterol . 2007 Jun; 13(23):3232-6. PMID: 17589903
Aim: To determine the efficacy of tacrolimus on clinical status, histopathological status and biochemical markers in patients with steroid refractory autoimmune hepatitis (AIH). Methods: Retrospectively, clinical parameters, biochemistry and histology...
10.
Eefsen M, Rasmussen A, Wulf H, Brock A, Hansen B
Liver Transpl . 2007 Mar; 13(5):655-7. PMID: 17377916
Erythropoietic protoporphyria (EPP) is a disease of the heme metabolism due to a deficiency of ferrochelatase, leading to accumulation of protoporphyrin (PPIX) in the erythrocyte (red blood cell [RBC]). The...