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Hans-Jorgen Frederiksen

Explore the profile of Hans-Jorgen Frederiksen including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 296
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Recent Articles
1.
Olesen N, Egesborg A, Frederiksen H, Kitchen C, Svendsen L, Olsen N, et al.
J Anaesthesiol Clin Pharmacol . 2023 Feb; 38(4):580-587. PMID: 36778814
Background And Aims: Anesthesia often reduces mean arterial pressure (MAP) to a level that may compromise cerebral blood flow. We evaluated whether phenylephrine treatment of anesthesia-induced hypotension affects internal carotid...
2.
Olesen N, Frederiksen H, Storkholm J, Hansen C, Svendsen L, Olsen N, et al.
Eur J Anaesthesiol . 2020 Mar; 37(6):482-490. PMID: 32175988
Background: Anaesthesia reduces mean arterial pressure (MAP), and to preserve organ perfusion, vasopressors are often used to maintain MAP above 60 mmHg. Cognitive dysfunction is common following major surgery and...
3.
Schultz N, Larsen P, Klarskov B, Plum L, Frederiksen H, Kehlet H, et al.
World J Surg . 2018 Jan; 42(6):1860-1866. PMID: 29302723
Background: Recent developments in perioperative pathophysiology and care have documented evidence-based, multimodal rehabilitation (fast-track) to hasten recovery and decrease morbidity and hospital stay in several major surgical procedures. The aim...
4.
Ambrus R, Svendsen L, Secher N, Runitz K, Frederiksen H, Svendsen M, et al.
Scand J Gastroenterol . 2016 Dec; 52(4):455-461. PMID: 27973925
Background: Reduced microvascular blood flow is related to anastomotic insufficiency following esophagectomy, emphasizing a need for intraoperative monitoring of the microcirculation. This study evaluated if laser speckle contrast imaging (LSCI)...
5.
Larsen F, Schmidt L, Bernsmeier C, Rasmussen A, Isoniemi H, Patel V, et al.
J Hepatol . 2015 Sep; 64(1):69-78. PMID: 26325537
Background & Aims: Acute liver failure (ALF) often results in cardiovascular instability, renal failure, brain oedema and death either due to irreversible shock, cerebral herniation or development of multiple organ...
6.
Bjerring P, Hauerberg J, Frederiksen H, Nielsen H, Clemmesen J, Larsen F
J Hepatol . 2012 Jun; 57(4):774-9. PMID: 22691571
Background & Aims: Patients with acute liver failure have a disturbed amino acid metabolism and a compromised oxidative metabolism in the brain. A limited number of clinically neuroprotective interventions are...
7.
Bjerring P, Hauerberg J, Jorgensen L, Frederiksen H, Tofteng F, Hansen B, et al.
J Hepatol . 2010 Aug; 53(6):1054-8. PMID: 20800925
Background & Aims: The pathogenesis of cerebral edema in acute liver failure is suggested, in in vitro and animal studies, to involve a compromised oxidative metabolism with a decrease in...
8.
Dethloff T, Tofteng F, Frederiksen H, Hojskov M, Hansen B, Larsen F
World J Gastroenterol . 2008 Apr; 14(13):2065-71. PMID: 18395908
Aim: To evaluate treatment safety and hemodynamic changes during a single 6-h treatment with the Prometheus liver assist system in a randomized, controlled study. Methods: Twenty-four patients were randomized to...
9.
Bjerring P, Hauerberg J, Frederiksen H, Jorgensen L, Hansen B, Tofteng F, et al.
Neurocrit Care . 2008 Feb; 9(1):3-7. PMID: 18250976
Aim: Hyperammonemia causes brain edema and high intracranial pressure (ICP) in acute liver failure (ALF) by accumulation of glutamine in brain. Since a high-level glutamine may compromise mitochondrial function, the...
10.
Eefsen M, Dethloff T, Frederiksen H, Hauerberg J, Hansen B, Larsen F
J Hepatol . 2007 Jun; 47(3):381-6. PMID: 17599633
Background/aims: Volume expansion and inotropic support with catecholamines are sometimes insufficient to ensure adequate blood pressure and cerebral perfusion in acute liver failure (ALF). The aim of this study was...