Martin A Shapiro
Overview
Explore the profile of Martin A Shapiro including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
43
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0
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Recent Articles
1.
Tran T, Ellsworth E, Sanchez J, Watson B, Stier M, Showalter H, et al.
Bioorg Med Chem Lett
. 2007 Jan;
17(5):1312-20.
PMID: 17196390
A series of 3-aminoquinazolinediones was synthesized and evaluated for its antibacterial and DNA gyrase activity. The SAR around the quinazolinedione core was explored and the optimal substitutions were combined to...
2.
Ellsworth E, Tran T, Showalter H, Sanchez J, Watson B, Stier M, et al.
J Med Chem
. 2006 Oct;
49(22):6435-8.
PMID: 17064062
The 3-aminoquinzolinediones represent a new series of antibacterial agents structurally related to the fluoroquinolones. They are inhibitors of bacterial gyrase and topoisomerase IV and demonstrate clinically useful antibacterial activity against...
3.
Tran T, Ellsworth E, Stier M, Domagala J, Showalter H, Gracheck S, et al.
Bioorg Med Chem Lett
. 2004 Sep;
14(17):4405-9.
PMID: 15357962
A series of 3-hydroxyquinazoline-2,4-diones was synthesized and evaluated for antibacterial activity. This series represents a novel addition to the DNA gyrase inhibitor class of antibacterials. Appropriate substitutions onto the core...