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Martin A Montecino

Explore the profile of Martin A Montecino including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 706
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Recent Articles
1.
Dashti P, Lewallen E, Gordon J, Montecino M, Davie J, Stein G, et al.
Bone . 2024 Feb; 181:117043. PMID: 38341164
Bone formation and homeostasis are controlled by environmental factors and endocrine regulatory cues that initiate intracellular signaling pathways capable of modulating gene expression in the nucleus. Bone-related gene expression is...
2.
Dashti P, Lewallen E, Gordon J, Montecino M, van Leeuwen J, Stein G, et al.
Bone Rep . 2023 Aug; 19:101704. PMID: 37593409
Osteogenic differentiation of mesenchymal cells is controlled by epigenetic enzymes that regulate post-translational modifications of histones. Compared to acetyl or methyltransferases, the physiological functions of protein arginine methyltransferases (PRMTs) in...
3.
Dashti P, van de Peppel J, Thaler R, Paradise C, Stein G, Montecino M, et al.
Gene . 2022 Oct; 851:146928. PMID: 36191822
Bone formation is controlled by histone modifying enzymes that regulate post-translational modifications on nucleosomal histone proteins and control accessibility of transcription factors to gene promoters required for osteogenesis. Enhancer of...
4.
Di Genova A, Nardocci G, Maldonado-Agurto R, Hodar C, Valdivieso C, Morales P, et al.
Genomics . 2021 Dec; 114(1):305-315. PMID: 34954349
Orestias ascotanensis (Cyprinodontidae) is a teleost pupfish endemic to springs feeding into the Ascotan saltpan in the Chilean Altiplano (3,700 m.a.s.l.) and represents an opportunity to study adaptations to high-altitude...
5.
Dudakovic A, Gluscevic M, Paradise C, Dudakovic H, Khani F, Thaler R, et al.
Gene . 2017 Jan; 609:28-37. PMID: 28132772
Epigenetic mechanisms control phenotypic commitment of mesenchymal stromal/stem cells (MSCs) into osteogenic, chondrogenic or adipogenic lineages. To investigate enzymes and chromatin binding proteins controlling the epigenome, we developed a hybrid...
6.
Dudakovic A, Camilleri E, Riester S, Paradise C, Gluscevic M, OToole T, et al.
J Biol Chem . 2016 Oct; 291(47):24594-24606. PMID: 27758858
Perturbations in skeletal development and bone degeneration may result in reduced bone mass and quality, leading to greater fracture risk. Bone loss is mitigated by bone protective therapies, but there...
7.
Grandy R, Whitfield T, Wu H, Fitzgerald M, VanOudenhove J, Zaidi S, et al.
Mol Cell Biol . 2015 Dec; 36(4):615-27. PMID: 26644406
Stem cell phenotypes are reflected by posttranslational histone modifications, and this chromatin-related memory must be mitotically inherited to maintain cell identity through proliferative expansion. In human embryonic stem cells (hESCs),...
8.
Dudakovic A, Camilleri E, Xu F, Riester S, McGee-Lawrence M, Bradley E, et al.
J Biol Chem . 2015 Oct; 290(46):27604-17. PMID: 26424790
Epigenetic control of gene expression is critical for normal fetal development. However, chromatin-related mechanisms that activate bone-specific programs during osteogenesis have remained underexplored. Therefore, we investigated the expression profiles of...
9.
Gordon J, Montecino M, Aqeilan R, Stein J, Stein G, Lian J
Curr Osteoporos Rep . 2014 Sep; 12(4):496-506. PMID: 25260661
Epigenetic regulation utilizes different mechanisms to convey heritable traits to progeny cells that are independent of DNA sequence, including DNA silencing, post-translational modifications of histone proteins, and the post-transcriptional modulation...
10.
Assar R, Montecino M, Maass A, Sherman D
Biosystems . 2014 Jun; 121:43-53. PMID: 24892552
In order to describe the dynamic behavior of a complex biological system, it is useful to combine models integrating processes at different levels and with temporal dependencies. Such combinations are...