Christopher R Paradise
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Explore the profile of Christopher R Paradise including associated specialties, affiliations and a list of published articles.
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41
Citations
739
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Recent Articles
1.
McGraw I, Wilson E, Behfar A, Paradise C, Rohrich R, Wyles S
Plast Reconstr Surg Glob Open
. 2024 Aug;
12(8):e6061.
PMID: 39157711
Exosomes, or extracellular vesicles, represent the latest cell-free addition to the regenerative medicine toolkit. In vitro preclinical studies have demonstrated the safety and efficacy of exosomes, which vary based on...
2.
Xuan W, Wang S, Alarcon-Calderon A, Bagwell M, Para R, Wang F, et al.
Transl Res
. 2024 Feb;
269:76-93.
PMID: 38325750
Chronic obstructive pulmonary disease (COPD) is a prevalent lung disease usually resulting from cigarette smoking (CS). Cigarette smoking induces oxidative stress, which causes inflammation and alveolar epithelial cell apoptosis and...
3.
Rolland T, Peterson T, Singh R, Rizzo S, Boroumand S, Shi A, et al.
NPJ Regen Med
. 2022 Nov;
7(1):65.
PMID: 36316357
No abstract available.
4.
Dashti P, van de Peppel J, Thaler R, Paradise C, Stein G, Montecino M, et al.
Gene
. 2022 Oct;
851:146928.
PMID: 36191822
Bone formation is controlled by histone modifying enzymes that regulate post-translational modifications on nucleosomal histone proteins and control accessibility of transcription factors to gene promoters required for osteogenesis. Enhancer of...
5.
Rolland T, Peterson T, Singh R, Rizzo S, Boroumand S, Shi A, et al.
NPJ Regen Med
. 2022 Sep;
7(1):58.
PMID: 36175423
Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these cases, precipitating ~200,000 surgical procedures annually. Continence...
6.
Dudakovic A, Jerez S, Deosthale P, Denbeigh J, Paradise C, Gluscevic M, et al.
Sci Rep
. 2022 Aug;
12(1):13361.
PMID: 35922466
High-throughput microRNA sequencing was performed during differentiation of MC3T3-E1 osteoblasts to develop working hypotheses for specific microRNAs that control osteogenesis. The expression data show that miR-101a, which targets the mRNAs...
7.
Proffer S, Paradise C, DeGrazia E, Halaas Y, Durairaj K, Somenek M, et al.
Aesthet Surg J
. 2022 Jun;
42(10):1185-1193.
PMID: 35689936
Background: Exosomes are regenerative mediators for skin rejuvenation. Human platelet extract (HPE) is an allogeneic exosome product derived from US-sourced, leukocyte-reduced apheresed platelets with consistent purity and potency. Objectives: The...
8.
Paradise C, Galvan M, Pichurin O, Jerez S, Kubrova E, Dehghani S, et al.
Bone
. 2021 Oct;
154:116234.
PMID: 34700039
Differentiation of multi-potent mesenchymal stromal cells (MSCs) is directed by the activities of lineage-specific transcription factors and co-factors. A subset of these proteins controls the accessibility of chromatin by recruiting...
9.
Paradise C, De La Vega R, Galvan M, Carrasco M, Thaler R, van Wijnen A, et al.
JBMR Plus
. 2021 Oct;
5(10):e10520.
PMID: 34693189
Bromodomain (BRD) proteins are histone code interpreters that recognize acetylated lysines and link the dynamic state of chromatin with the transcriptional machinery. Here, we demonstrate that ablation of the Brd4...
10.
Galea G, Paradise C, Meakin L, Camilleri E, Taipaleenmaki H, Stein G, et al.
Gene
. 2021 Sep;
763S:100027.
PMID: 34493364
Mechanical loading-related strains trigger bone formation by osteoblasts while suppressing resorption by osteoclasts, uncoupling the processes of formation and resorption. Osteocytes may orchestrate this process in part by secreting sclerostin...