Martha Sosa-Macias
Overview
Explore the profile of Martha Sosa-Macias including associated specialties, affiliations and a list of published articles.
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49
Citations
316
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Recent Articles
1.
Torso N, Rodrigues-Soares F, Altamirano C, Ramirez-Roa R, Sosa-Macias M, Galaviz-Hernandez C, et al.
Drug Metab Pers Ther
. 2024 Dec;
39(4):201-206.
PMID: 39663234
The CYP2C19 enzyme is implicated in the metabolism of several clinically used drugs. Its phenotype is usually predicted by genotyping and indicates the expected enzymatic activity for each patient. However,...
2.
Sosa-Macias M, Fricke-Galindo I, Farinas H, Monterde L, Dolores Ruiz-Cruz E, Molina-Guarneros J, et al.
Pharmacogenomics
. 2023 Aug;
24(9):489-492.
PMID: 37529900
The Ibero-American Network of Pharmacogenetics and Pharmacogenomics (RIBEF) studies Latin American populations to benefit from the implementation of personalized medicine. Since 2006, it has studied ethnicity to apply pharmacogenetics knowledge...
3.
Carrasco-Wong I, Gonzalez-Ortiz M, Araujo G, Lima V, Giachini F, Stojanova J, et al.
Adv Exp Med Biol
. 2023 Jul;
1428:287-307.
PMID: 37466779
Currently, more than 100,000 papers had been published studying the placenta in both physiological and pathological contexts. However, relevant health conditions affecting placental function, mostly found in low-income countries, should...
4.
Macias-Salas A, Sosa-Macias M, Barragan-Zuniga L, Blanco-Castaneda R, Damiano A, Garcia-Robles R, et al.
Placenta
. 2023 Mar;
135:1-6.
PMID: 36878143
Introduction: Preeclampsia is a leading cause of maternal and fetal morbidity in low- and middle-income countries, including those in Latin America. Placental vascular alterations are crucial in the pathophysiology of...
5.
Garcia-Ortiz H, Barajas-Olmos F, Contreras-Cubas C, Reynolds A, Flores-Huacuja M, Snow M, et al.
Genes (Basel)
. 2022 Dec;
13(12).
PMID: 36553518
Few studies have addressed how selective pressures have shaped the genetic structure of the current Native American populations, and they have mostly limited their inferences to admixed Latin American populations....
6.
Moreira R, Saraiva-Duarte J, Pereira A, Sosa-Macias M, Galaviz-Hernandez C, Santolalla M, et al.
Clin Transl Sci
. 2022 Mar;
15(6):1400-1405.
PMID: 35266293
PDE4B (phosphodiesterase-4B) has an important role in cancer and in pharmacology of some disorders, such as inflammatory diseases. Remarkably in Native Americans, PDE4B variants are associated with acute lymphoblastic leukemia...
7.
Barragan-Zuniga L, Marchat L, Carrasco-Wong I, Blanco-Castaneda R, Salas-Pacheco J, Simental-Mendia L, et al.
Front Med (Lausanne)
. 2022 Mar;
9:795309.
PMID: 35252239
Preeclampsia (PE) is a leading cause of maternal-fetal mortality worldwide, and obesity is an important risk factor. Genes associated with pathophysiological events common to preeclampsia and obesity, such as ,...
8.
Blanco-Castaneda R, Zapata-Vazquez Y, Lazalde-Ramos B, Enriquez-Mendiola D, Lares-Asseff I, Galaviz-Hernandez C, et al.
Epilepsia
. 2022 Feb;
63(5):1266-1275.
PMID: 35174498
Objective: Levetiracetam (LEV) is an antiseizure medication prescribed to women during childbearing age. The impact of LEV on placental transporters is poorly understood. This study aimed to assess the effect...
9.
Garcia-Ortiz H, Barajas-Olmos F, Contreras-Cubas C, Cid-Soto M, Cordova E, Centeno-Cruz F, et al.
Nat Commun
. 2021 Oct;
12(1):5942.
PMID: 34642312
The genetic makeup of Indigenous populations inhabiting Mexico has been strongly influenced by geography and demographic history. Here, we perform a genome-wide analysis of 716 newly genotyped individuals from 60...
10.
Carrasco-Wong I, Aguilera-Olguin M, Escalona-Rivano R, Chiarello D, Barragan-Zuniga L, Sosa-Macias M, et al.
Placenta
. 2021 May;
113:57-66.
PMID: 34053733
Preeclampsia is a pregnancy-specific syndrome characterized by a sudden increase in blood pressure accompanied by proteinuria and/or maternal multi-system damage associated to poor fetal outcome. In early-onset preeclampsia, utero-placental perfusion...