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Marten Michaelis

Explore the profile of Marten Michaelis including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 220
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Recent Articles
1.
Baddela V, Michaelis M, Tao X, Koczan D, Brenmoehl J, Vanselow J
Reproduction . 2024 Dec; 169(2). PMID: 39665647
In Brief: PI3K-AKT signaling activates steroidogenesis by inducing estradiol and progesterone production, while MEK-ERK1/2 signaling regulates steroidogenesis by inhibiting estradiol and inducing progesterone production in granulosa cells (GCs). Both pathways...
2.
Tao X, Rahimi M, Michaelis M, Gors S, Brenmoehl J, Vanselow J, et al.
Sci Rep . 2024 Apr; 14(1):9888. PMID: 38688953
Fatty acids have been shown to modulate glucose metabolism in vitro and in vivo. However, there is still a need for substantial evidence and mechanistic understanding in many cell types...
3.
Baddela V, Michaelis M, Tao X, Koczan D, Vanselow J
Life Sci Alliance . 2023 Aug; 6(10). PMID: 37532283
Estradiol and progesterone are the primary sex steroids produced by the ovary. Upon luteinizing hormone surge, estradiol-producing granulosa cells convert into progesterone-producing cells and eventually become large luteal cells of...
4.
Calanni-Pileri M, Michaelis M, Langhammer M, Tognetti P, Weitzel J
Biomedicines . 2023 May; 11(5). PMID: 37239110
Declining human fertility worldwide is an attractive research target for the search for "high fertility" genes and pathways to counteract this problem. To study these genes and pathways for high...
5.
Ludwig C, Bohleber S, Lapp R, Rebl A, Wirth E, Langhammer M, et al.
J Ovarian Res . 2023 Feb; 16(1):32. PMID: 36739419
The development and maturation of ovarian follicles is a complex and highly regulated process, which is essential for successful ovulation. During recent decades, several mouse models provided insights into the...
6.
Calanni-Pileri M, Weitzel J, Dannenberger D, Langhammer M, Michaelis M
Int J Mol Sci . 2022 Sep; 23(18). PMID: 36142150
In recent decades, fertility traits in humans as well as in farm animals have decreased worldwide. As such, it is imperative to know more about the genetics and physiology of...
7.
Baddela V, Michaelis M, Sharma A, Plinski C, Viergutz T, Vanselow J
J Biol Chem . 2022 Sep; 298(10):102477. PMID: 36096202
Ovarian cycle is controlled by circulating levels of the steroid hormone 17-β-estradiol, which is predominantly synthesized by the granulosa cells (GCs) of ovarian follicles. Our earlier studies showed that unsaturated...
8.
Calanni-Pileri M, Weitzel J, Langhammer M, Michaelis M
Reprod Domest Anim . 2022 Jun; 57(10):1198-1207. PMID: 35765745
Dummerstorf fertility lines FL1 and FL2 represent two models of enhanced fertility characterized by the doubling of the litter size compared with an unselected control population (ctrl line, Dummerstorf FztDU)....
9.
Ludwig C, Bohleber S, Rebl A, Wirth E, Venuto M, Langhammer M, et al.
J Mol Endocrinol . 2022 Apr; 69(1):285-298. PMID: 35388794
The Dummerstorf high-fertility mouse line FL1 is a worldwide unique selection experiment for increased female reproductive performance. After more than 190 generations of selection, these mice doubled the amount of...
10.
Calanni-Pileri M, Weitzel J, Langhammer M, Wytrwat E, Michaelis M
Reprod Domest Anim . 2022 Feb; 57(6):577-586. PMID: 35152512
Mouse models of decreased fertility mainly support scientific knowledge in the field of reproductive biology. In this study, we changed the perspective, using Dummerstorf high-fertility mouse lines FL1 and FL2...