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Marta Baldrighi

Explore the profile of Marta Baldrighi including associated specialties, affiliations and a list of published articles. Areas
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Citations 348
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Recent Articles
1.
Baldrighi M, Doreth C, Li Y, Zhao X, Warner E, Chenoweth H, et al.
J Clin Invest . 2023 Sep; 133(21). PMID: 37698938
Unabated activation of the NLR family pyrin domain-containing 3 (NLRP3) inflammasome is linked with the pathogenesis of various inflammatory disorders. Polo-like kinase 1 (PLK1) has been widely studied for its...
2.
Iqbal A, Baldrighi M, Murdoch J, Fleming A, Wilkinson C
Biol Open . 2020 Sep; 9(10). PMID: 32878882
Protein aggregates are the pathogenic hallmarks of many different neurodegenerative diseases and include the accumulation of α-synuclein, the main component of Lewy bodies found in Parkinson's disease. Aggresomes are closely-related,...
3.
Cano-Gamez E, Soskic B, Roumeliotis T, So E, Smyth D, Baldrighi M, et al.
Nat Commun . 2020 Apr; 11(1):1801. PMID: 32286271
Naïve CD4 T cells coordinate the immune response by acquiring an effector phenotype in response to cytokines. However, the cytokine responses in memory T cells remain largely understudied. Here we...
4.
Baldrighi M, Mallat Z, Li X
Atherosclerosis . 2017 Nov; 267:127-138. PMID: 29126031
Atherosclerosis is the major cause of death and disability. Atherosclerotic plaques are characterized by a chronic sterile inflammation in the large blood vessels, where lipid-derived and damage-associated molecular patterns play...
5.
Bolognesi B, Gotor N, Dhar R, Cirillo D, Baldrighi M, Tartaglia G, et al.
Cell Rep . 2016 Jun; 16(1):222-231. PMID: 27320918
Multiple human diseases are associated with a liquid-to-solid phase transition resulting in the formation of amyloid fibers or protein aggregates. Here, we present an alternative mechanism for cellular toxicity based...