Markus Waldeck-Weiermair
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Explore the profile of Markus Waldeck-Weiermair including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Deak A, Jean-Quartier C, Bondarenko A, Groschner L, Malli R, Graier W, et al.
Methods Mol Biol
. 2021 Jun;
2276:173-191.
PMID: 34060041
Mitochondrial Ca uptake regulates mitochondrial function and contributes to cell signaling. Accordingly, quantifying mitochondrial Ca signals and elaborating the mechanisms that accomplish mitochondrial Ca uptake are essential to gain our...
12.
Kruger C, Waldeck-Weiermair M, Kaynert J, Pokrant T, Komaragiri Y, Otto O, et al.
Redox Biol
. 2021 Apr;
43:101962.
PMID: 33892285
Peroxiporins are distinct aquaporins (AQP) which, beside water, also facilitate the bidirectional transport of hydrogen peroxide (HO) across cellular membranes. HO serves as the major reactive oxygen species that mediates...
13.
Koshenov Z, Oflaz F, Hirtl M, Bachkoenig O, Rost R, Osibow K, et al.
Mitochondrion
. 2020 Oct;
55:164-173.
PMID: 33069910
Considering the versatile functions attributed to uncoupling protein 2 (UCP2) in health and disease, a profound understanding of the protein's molecular actions under physiological and pathophysiological conditions is indispensable. This...
14.
Saeedi Saravi S, Eroglu E, Waldeck-Weiermair M, Sorrentino A, Steinhorn B, Belousov V, et al.
Redox Biol
. 2020 Jun;
36:101605.
PMID: 32590330
Hydrogen peroxide (HO) modulates critical phosphorylation pathways in vascular endothelial cells, many of which affect endothelial nitric oxide synthase (eNOS) signal transduction. Both intracellular and extracellular sources of HO have...
15.
Ramadani-Muja J, Gottschalk B, Pfeil K, Burgstaller S, Rauter T, Bischof H, et al.
Cells
. 2019 Dec;
8(12).
PMID: 31817668
Mitochondrial sirtuins (Sirts) control important cellular processes related to stress. Despite their regulatory importance, however, the dynamics and subcellular distributions of Sirts remain debatable. Here, we investigate the subcellular localization...
16.
Waldeck-Weiermair M, Gottschalk B, Madreiter-Sokolowski C, Ramadani-Muja J, Ziomek G, Klec C, et al.
Front Cell Neurosci
. 2019 Oct;
13:449.
PMID: 31636543
Mitochondrial Ca uptake into the mitochondrial matrix is a well-established mechanism. However, the sub-organellar Ca kinetics remain elusive. In the present work we identified novel site-specific targeting sequences for the...
17.
Klec C, Madreiter-Sokolowski C, Ziomek G, Stryeck S, Sachdev V, Duta-Mare M, et al.
Cell Physiol Biochem
. 2019 Sep;
53(3):573-586.
PMID: 31529929
Background/aims: In our recent work, the importance of GSK3β-mediated phosphorylation of presenilin-1 as crucial process to establish a Ca leak in the endoplasmic reticulum and, subsequently, the pre-activation of resting...
18.
Gottschalk B, Klec C, Leitinger G, Bernhart E, Rost R, Bischof H, et al.
Nat Commun
. 2019 Aug;
10(1):3732.
PMID: 31427612
Recently identified core proteins (MICU1, MCU, EMRE) forming the mitochondrial Ca uniporter complex propelled investigations into its physiological workings. Here, we apply structured illumination microscopy to visualize and localize these...
19.
Depaoli M, Bischof H, Eroglu E, Burgstaller S, Ramadani-Muja J, Rauter T, et al.
Pharmacol Ther
. 2019 Jun;
202:98-119.
PMID: 31176696
The interplay of metabolic and signaling processes is prerequisite for the functionality of cells. Any disturbances may have severe consequences, resulting in the development of diseases. However, the complex coordination...
20.
Live-Cell Imaging of Physiologically Relevant Metal Ions Using Genetically Encoded FRET-Based Probes
Bischof H, Burgstaller S, Waldeck-Weiermair M, Rauter T, Schinagl M, Ramadani-Muja J, et al.
Cells
. 2019 May;
8(5).
PMID: 31121936
Essential biochemical reactions and processes within living organisms are coupled to subcellular fluctuations of metal ions. Disturbances in cellular metal ion homeostasis are frequently associated with pathological alterations, including neurotoxicity...