Marko J Pregel
Overview
Explore the profile of Marko J Pregel including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
25
Followers
0
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Recent Articles
1.
Huichalaf C, Perfitt T, Kuperman A, Gooch R, Kovi R, Brenneman K, et al.
Mol Ther Methods Clin Dev
. 2022 Mar;
24:367-378.
PMID: 35252470
Friedreich's ataxia is a rare disorder resulting from deficiency of frataxin, a mitochondrial protein implicated in the synthesis of iron-sulfur clusters. Preclinical studies in mice have shown that gene therapy...
2.
Liu J, Berg A, Wang Y, Jantarajit W, Sutcliffe K, Stevens E, et al.
Br J Pharmacol
. 2021 Oct;
179(7):1319-1337.
PMID: 34644413
Background And Purpose: Cystic fibrosis transmembrane conductance regulator (CFTR) potentiators are small molecules developed to treat the genetic disease cystic fibrosis (CF). They interact directly with CFTR Cl channels at...
3.
Hirth B, Qiao S, Cuff L, Cochran B, Pregel M, Gregory J, et al.
Bioorg Med Chem Lett
. 2005 Apr;
15(8):2087-91.
PMID: 15808474
A series of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase chloride transport in cells expressing mutant cystic fibrosis transmembrane conductance regulator (CFTR) protein has been identified from our compound library. Analoging efforts...