Mark McNiven
Overview
Explore the profile of Mark McNiven including associated specialties, affiliations and a list of published articles.
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8
Citations
330
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0
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Recent Articles
1.
Webb M, Sangsuwannukul T, van Vloten J, Evgin L, Kendall B, Tonne J, et al.
Nat Commun
. 2024 Jun;
15(1):5442.
PMID: 38937436
Although patients benefit from immune checkpoint inhibition (ICI) therapy in a broad variety of tumors, resistance may arise from immune suppressive tumor microenvironments (TME), which is particularly true of hepatocellular...
2.
Vile R, Webb M, van Vloten J, Evgin L, Sangsuwannukul T, Kendall B, et al.
Res Sq
. 2023 Dec;
PMID: 38045348
Although immune checkpoint inhibition (ICI) has produced profound survival benefits in a broad variety of tumors, a proportion of patients do not respond. Treatment failure is in part due to...
3.
Kottke T, Tonne J, Evgin L, Driscoll C, van Vloten J, Jennings V, et al.
Nat Commun
. 2021 Mar;
12(1):1930.
PMID: 33772027
In our clinical trials of oncolytic vesicular stomatitis virus expressing interferon beta (VSV-IFNβ), several patients achieved initial responses followed by aggressive relapse. We show here that VSV-IFNβ-escape tumors predictably express...
4.
Unsworth K, Mazurkiewicz P, Senf F, Zettl M, McNiven M, Way M, et al.
Cell Microbiol
. 2006 Sep;
9(2):438-49.
PMID: 16965516
After attaching to human intestinal epithelial cells, enteropathogenic Escherichia coli (EPEC) induces the formation of an actin-rich pedestal-like structure. The signalling pathway leading to pedestal formation is initiated by the...
5.
Unsworth K, Way M, McNiven M, Machesky L, Holden D
Cell Microbiol
. 2004 Oct;
6(11):1041-55.
PMID: 15469433
Salmonella enterica serovar Typhimurium (S. typhimurium) induces actin assembly both during invasion of host cells and during the course of intracellular bacterial replication. In this study, we investigated the involvement...
6.
Trushina E, Dyer R, Badger 2nd J, Ure D, Eide L, Tran D, et al.
Mol Cell Biol
. 2004 Sep;
24(18):8195-209.
PMID: 15340079
Recent data in invertebrates demonstrated that huntingtin (htt) is essential for fast axonal trafficking. Here, we provide direct and functional evidence that htt is involved in fast axonal trafficking in...
7.
Yoon Y, Pitts K, McNiven M
Mol Biotechnol
. 2002 Jul;
21(3):241-50.
PMID: 12102548
Microfilaments, intermediate filaments, and microtubules are three major cytoskeletal systems providing cells with stability to maintain proper shape. Although the word "cytoskeleton" implicates rigidity, it is quite dynamic exhibiting constant...
8.
Kamitani A, Yamada H, Kinuta M, Watanabe M, Li S, Matsukawa T, et al.
Biochem Biophys Res Commun
. 2002 Jun;
294(2):261-7.
PMID: 12051704
Dynamin 2 and dynamin 3 are highly expressed in testis. However, their functions in the tissue remain unclear. Considering that dynamin 1, neuron-specific isoform of dynamin, plays a pivotal role...