Mark Labow
Overview
Explore the profile of Mark Labow including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
24
Citations
1367
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Casalino E, Stine L, Corin A, Thai C, Quiroz J, Wilson S, et al.
SLAS Discov
. 2022 May;
27(6):349-357.
PMID: 35580766
Small-molecule high-throughput screening (HTS) campaigns have frequently been used to identify lead molecules that can alter expression of disease-relevant proteins in cell-based assays. However, most cell-based HTS assays require short...
2.
Matyskiela M, Zhu J, Baughman J, Clayton T, Slade M, Wong H, et al.
ACS Chem Biol
. 2020 Nov;
15(12):3149-3158.
PMID: 33206504
There is a growing interest in using targeted protein degradation as a therapeutic modality in view of its potential to expand the druggable proteome. One avenue to using this modality...
3.
Rothman D, Gao X, George E, Rasmusson T, Bhatia D, Alimov I, et al.
Chem Biol
. 2015 Sep;
22(9):1228-37.
PMID: 26364931
In an attempt to identify novel therapeutics and mechanisms to differentially kill tumor cells using phenotypic screening, we identified N-benzyl indole carbinols (N-BICs), synthetic analogs of the natural product indole-3-carbinol...
4.
Nicholson T, Singh A, Su H, Hevi S, Wang J, Bajko J, et al.
PLoS One
. 2013 May;
8(4):e60913.
PMID: 23637775
Lysine-specific demethylase 1 (Lsd1/Aof2/Kdm1a), the first enzyme with specific lysine demethylase activity to be described, demethylates histone and non-histone proteins and is essential for mouse embryogenesis. Lsd1 interacts with numerous...
5.
Mastyugin V, McWhinnie E, Labow M, Buxton F
Drug Discov Today
. 2013 Apr;
Suppl:43-9.
PMID: 23570165
By combining the use of BD Biosciences FluoroBlok membrane-based Boyden chambers with the Cellomics HCS ArrayScan, a more sensitive method for measuring cell migration has been developed. This assay is...
6.
Britschgi A, Bill A, Brinkhaus H, Rothwell C, Clay I, Duss S, et al.
Proc Natl Acad Sci U S A
. 2013 Feb;
110(11):E1026-34.
PMID: 23431153
The calcium-activated chloride channel anoctamin 1 (ANO1) is located within the 11q13 amplicon, one of the most frequently amplified chromosomal regions in human cancer, but its functional role in tumorigenesis...
7.
Nicholson T, Su H, Hevi S, Wang J, Bajko J, Li M, et al.
Cell Res
. 2012 Apr;
PMID: 22491473
No abstract available.
8.
Nicholson T, Su H, Hevi S, Wang J, Bajko J, Li M, et al.
Cell Res
. 2011 Dec;
PMID: 22143567
Lysine-specific demethylase 1 (LSD1/AOF2/KDM1A), the first enzyme with specific lysine demethylase activity to be described, demethylates histone and non-histone proteins and is essential for mouse embryogenesis. LSD1 interacts with numerous...
9.
Chen J, Shen Q, Labow M, Gaither L
Cancer Res
. 2011 Apr;
71(12):4280-91.
PMID: 21527556
RAS mutations occur in more than 30% of all human cancers but efforts to directly target mutant RAS signaling as a cancer therapy have yet to succeed. As alternative strategies,...
10.
Gottar-Guillier M, Dodeller F, Huesken D, Iourgenko V, Mickanin C, Labow M, et al.
J Immunol
. 2011 Apr;
186(10):6014-23.
PMID: 21471444
Inflammatory cytokines like TNF play a central role in autoimmune disorders such as rheumatoid arthritis. We identified the tyrosine kinase bone marrow kinase on chromosome X (BMX) as an essential...