Mark J Arcario
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Explore the profile of Mark J Arcario including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
356
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Recent Articles
1.
Dalal V, Arcario M, Petroff 2nd J, Tan B, Dietzen N, Rau M, et al.
Nat Commun
. 2024 Jan;
15(1):25.
PMID: 38167383
Lipid nanodiscs have become a standard tool for studying membrane proteins, including using single particle cryo-electron microscopy (cryo-EM). We find that reconstituting the pentameric ligand-gated ion channel (pLGIC), Erwinia ligand-gated...
2.
Cheng W, Arcario M, Petroff 2nd J
Front Physiol
. 2022 Jan;
12:798102.
PMID: 35069257
Lipids modulate the function of many ion channels, possibly through direct lipid-protein interactions. The recent outpouring of ion channel structures by cryo-EM has revealed many lipid binding sites. Whether these...
3.
Dietzen N, Arcario M, Chen L, Petroff 2nd J, Moreland K, Krishnan K, et al.
Elife
. 2022 Jan;
11.
PMID: 34982031
Polyunsaturated fatty acids (PUFAs) inhibit pentameric ligand-gated ion channels (pLGICs) but the mechanism of inhibition is not well understood. The PUFA, docosahexaenoic acid (DHA), inhibits agonist responses of the pLGIC,...
4.
Emmert D, Arcario M, Maranhao B, Reidy A
Curr Opin Anaesthesiol
. 2021 Oct;
35(1):53-59.
PMID: 34669613
Purpose Of Review: With an aging cardiac surgery population, prefrail and frail patients are becoming more common. Anesthesiologists will be faced with the decision of how best to provide care...
5.
Arcario M, Lou S, Taylor P, Gregory S
J Cardiothorac Vasc Anesth
. 2021 Jan;
35(11):3340-3349.
PMID: 33431271
The sinuses of Valsalva are outpouchings in the aortic root just distal to the aortic valve that serve several physiologic functions. Aneurysm of this segment of the aorta is quite...
6.
Arcario M, Mayne C, Tajkhorshid E
J Biol Chem
. 2017 Apr;
292(23):9480-9492.
PMID: 28420728
General anesthetics exert their effects on the central nervous system by acting on ion channels, most notably pentameric ligand-gated ion channels. Although numerous studies have focused on pentameric ligand-gated ion...
7.
Mayne C, Arcario M, Mahinthichaichan P, Baylon J, Vermaas J, Navidpour L, et al.
Biochim Biophys Acta
. 2016 May;
1858(10):2290-2304.
PMID: 27163493
The cellular membrane constitutes the first element that encounters a wide variety of molecular species to which a cell might be exposed. Hosting a large number of structurally and functionally...
8.
Baylon J, Vermaas J, Muller M, Arcario M, Pogorelov T, Tajkhorshid E
Biochim Biophys Acta
. 2016 Mar;
1858(7 Pt B):1573-83.
PMID: 26940626
Peripheral membrane proteins are structurally diverse proteins that are involved in fundamental cellular processes. Their activity of these proteins is frequently modulated through their interaction with cellular membranes, and as...
9.
Vermaas J, Baylon J, Arcario M, Muller M, Wu Z, Pogorelov T, et al.
J Membr Biol
. 2015 May;
248(3):563-82.
PMID: 25998378
Biological membranes constitute a critical component in all living cells. In addition to providing a conducive environment to a wide range of cellular processes, including transport and signaling, mounting evidence...
10.
Blanchard A, Arcario M, Schulten K, Tajkhorshid E
Biophys J
. 2014 Nov;
107(9):2112-21.
PMID: 25418096
The SNARE complex plays a vital role in vesicle fusion arising during neuronal exocytosis. Key components in the regulation of SNARE complex formation, and ultimately fusion, are the transmembrane and...