Mark Alber
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Explore the profile of Mark Alber including associated specialties, affiliations and a list of published articles.
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56
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821
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Recent Articles
1.
Tsai K, Zhou Z, Yang J, Xu Z, Xu S, Zandi R, et al.
PLoS Comput Biol
. 2024 Sep;
20(9):e1012491.
PMID: 39348424
Understanding the mechanisms of the cellular aging processes is crucial for attempting to extend organismal lifespan and for studying age-related degenerative diseases. Yeast cells divide through budding, providing a classical...
2.
Cannon W, Britton S, Banwarth-Kuhn M, Alber M
J Chem Phys
. 2024 Jun;
160(21).
PMID: 38842085
We demonstrate and characterize a first-principles approach to modeling the mass action dynamics of metabolism. Starting from a basic definition of entropy expressed as a multinomial probability density using Boltzmann...
3.
Kumar N, Rangel Ambriz J, Tsai K, Mim M, Flores-Flores M, Chen W, et al.
Nat Commun
. 2024 Mar;
15(1):2477.
PMID: 38509115
How a developing organ robustly coordinates the cellular mechanics and growth to reach a final size and shape remains poorly understood. Through iterations between experiments and model simulations that include...
4.
Tsai K, Zhou Z, Yang J, Xu Z, Xu S, Zandi R, et al.
bioRxiv
. 2024 Mar;
PMID: 38464259
Understanding the mechanisms of cellular aging processes is crucial for attempting to extend organismal lifespan and for studying age-related degenerative diseases. Yeast cells divide through budding, providing a classical biological...
5.
Michael C, Pancaldi F, Britton S, Kim O, Peshkova A, Vo K, et al.
Commun Biol
. 2023 Aug;
6(1):869.
PMID: 37620422
While blood clot formation has been relatively well studied, little is known about the mechanisms underlying the subsequent structural and mechanical clot remodeling called contraction or retraction. Impairment of the...
6.
Michael C, Banwarth-Kuhn M, Rodriguez K, Ta C, Roy-Chowdhury A, Chen W, et al.
J R Soc Interface
. 2023 Jun;
20(203):20230173.
PMID: 37282588
In plants, the robust maintenance of tissue structure is crucial to supporting its functionality. The multi-layered shoot apical meristem (SAM) of containing stem cells is an approximately radially symmetric tissue...
7.
Ramezani A, Britton S, Zandi R, Alber M, Nematbakhsh A, Chen W
NPJ Syst Biol Appl
. 2023 May;
9(1):16.
PMID: 37210381
The exact mechanism controlling cell growth remains a grand challenge in developmental biology and regenerative medicine. The Drosophila wing disc tissue serves as an ideal biological model to study mechanisms...
8.
Rodriguez K, Do A, Senay-Aras B, Perales M, Alber M, Chen W, et al.
Sci Adv
. 2022 Aug;
8(32):eabo6157.
PMID: 35947668
Gene expression specificity of homeobox transcription factors has remained paradoxical. WUSCHEL activates and represses transcription at lower and higher concentrations, respectively. We use computational modeling and experimental analysis to investigate...
9.
Banwarth-Kuhn M, Rodriguez K, Michael C, Ta C, Plong A, Bourgain-Chang E, et al.
PLoS Comput Biol
. 2022 Jun;
18(6):e1010199.
PMID: 35727850
Stem cell maintenance in multilayered shoot apical meristems (SAMs) of plants requires strict regulation of cell growth and division. Exactly how the complex milieu of chemical and mechanical signals interact...
10.
Pancaldi F, Kim O, Weisel J, Alber M, Xu Z
Curr Opin Biomed Eng
. 2022 Apr;
22.
PMID: 35386550
Fibrin deformation and interaction of fibrin with other blood components play critical roles in hemostasis and thrombosis. In this review, computational and mathematical biomechanical models of fibrin network deformation and...