Marjan E Askarian-Amiri
Overview
Explore the profile of Marjan E Askarian-Amiri including associated specialties, affiliations and a list of published articles.
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18
Citations
1596
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Recent Articles
11.
Askarian-Amiri M, Seyfoddin V, Smart C, Wang J, Kim J, Hansji H, et al.
PLoS One
. 2014 Jul;
9(7):e102140.
PMID: 25006803
The transcription factor SOX2 is essential for maintaining pluripotency in a variety of stem cells. It has important functions during embryonic development, is involved in cancer stem cell maintenance, and...
12.
Dmello S, Flanagan J, Green T, Leung E, Askarian-Amiri M, Joseph W, et al.
Front Oncol
. 2014 Jan;
3:333.
PMID: 24455489
Previous whole-exome sequencing has demonstrated that melanoma tumors harbor mutations in the GRIN2A gene. GRIN2A encodes the regulatory GluN2A subunit of the glutamate-gated N-methyl-d-aspartate receptor (NMDAR), involvement of which in...
13.
Askarian-Amiri M, Crawford J, French J, Smart C, Smith M, Clark M, et al.
RNA
. 2011 Apr;
17(5):878-91.
PMID: 21460236
Long noncoding RNAs (lncRNAs) are increasingly recognized to play major regulatory roles in development and disease. To identify novel regulators in breast biology, we identified differentially regulated lncRNAs during mouse...
14.
Mercer T, Dinger M, Bracken C, Kolle G, Szubert J, Korbie D, et al.
Genome Res
. 2010 Nov;
20(12):1639-50.
PMID: 21045082
The complexity of the eukaryotic transcriptome is generated by the interplay of transcription initiation, termination, alternative splicing, and other forms of post-transcriptional modification. It was recently shown that RNA transcripts...
15.
Amaral P, Neyt C, Wilkins S, Askarian-Amiri M, Sunkin S, Perkins A, et al.
RNA
. 2009 Sep;
15(11):2013-27.
PMID: 19767420
The Sox2 gene is a key regulator of pluripotency embedded within an intron of a long noncoding RNA (ncRNA), termed Sox2 overlapping transcript (Sox2ot), which is transcribed in the same...
16.
Dinger M, Amaral P, Mercer T, Pang K, Bruce S, Gardiner B, et al.
Genome Res
. 2008 Jun;
18(9):1433-45.
PMID: 18562676
The transcriptional networks that regulate embryonic stem (ES) cell pluripotency and lineage specification are the subject of considerable attention. To date such studies have focused almost exclusively on protein-coding transcripts....
17.
Poole E, Young D, Askarian-Amiri M, Scarlett D, Tate W
Cell Res
. 2007 Jul;
17(7):591-607.
PMID: 17621307
The decoding release factor (RF) triggers termination of protein synthesis by functionally mimicking a tRNA to span the decoding centre and the peptidyl transferase centre (PTC) of the ribosome. Structurally,...
18.
Poole E, Askarian-Amiri M, Major L, McCaughan K, Scarlett D, Wilson D, et al.
Prog Nucleic Acid Res Mol Biol
. 2003 Sep;
74:83-121.
PMID: 14510074
Molecular mimicry was a concept that was revived as we understood more about the ligands that bound to the active center of the ribosome, and the characteristics of the active...