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» Authors » Marit E Geijer

Marit E Geijer

Explore the profile of Marit E Geijer including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 225
Followers 0
Related Specialties
Cell Biology
Molecular Biology
Biochemistry
Top 10 Co-Authors
Roel C Janssens
Jurgen A Marteijn
Barbara Steurer
Arjan F Theil
Adriaan B Houtsmuller
Bart Geverts
Rene Bernards
Hannes Lans
Bastiaan Evers
Karel Bezstarosti
Published In
Nat Cell Biol
Proc Natl Acad Sci U S A
EMBO Rep
Toxicol Sci
DNA Repair (Amst)
Affiliations
Soon will be listed here.
Recent Articles
1.
DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II
Steurer B, Janssens R, Geijer M, Aprile-Garcia F, Geverts B, Theil A, et al.
Nat Commun . 2022 Jun; 13(1):3624. PMID: 35750669
The precise regulation of RNA Polymerase II (Pol II) transcription after genotoxic stress is crucial for proper execution of the DNA damage-induced stress response. While stalling of Pol II on...
2.
TubulinTracker, a Novel In Vitro Reporter Assay to Study Intracellular Microtubule Dynamics, Cell Cycle Progression, and Aneugenicity
Geijer M, Moelijker N, Zhang G, Derr R, Osterlund T, Hendriks G, et al.
Toxicol Sci . 2022 Jan; 186(2):288-297. PMID: 35094094
Aneuploidy is characterized by the presence of an abnormal number of chromosomes and is a common hallmark of cancer. However, exposure to aneugenic compounds does not necessarily lead to cancer....
3.
Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
Geijer M, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, et al.
Nat Cell Biol . 2021 Jun; 23(7):809. PMID: 34163038
No abstract available.
4.
Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability
Geijer M, Zhou D, Selvam K, Steurer B, Mukherjee C, Evers B, et al.
Nat Cell Biol . 2021 Jun; 23(6):608-619. PMID: 34108662
Correct transcription is crucial for life. However, DNA damage severely impedes elongating RNA polymerase II, causing transcription inhibition and transcription-replication conflicts. Cells are equipped with intricate mechanisms to counteract the...
5.
What happens at the lesion does not stay at the lesion: Transcription-coupled nucleotide excision repair and the effects of DNA damage on transcription in cis and trans
Geijer M, Marteijn J
DNA Repair (Amst) . 2018 Sep; 71:56-68. PMID: 30195642
Unperturbed transcription of eukaryotic genes by RNA polymerase II (Pol II) is crucial for proper cell function and tissue homeostasis. However, the DNA template of Pol II is continuously challenged...
6.
DNA damage-induced replication stress results in PA200-proteasome-mediated degradation of acetylated histones
Mandemaker I, Geijer M, Kik I, Bezstarosti K, Rijkers E, Raams A, et al.
EMBO Rep . 2018 Aug; 19(10). PMID: 30104204
Histone acetylation influences protein interactions and chromatin accessibility and plays an important role in the regulation of transcription, replication, and DNA repair. Conversely, DNA damage affects these crucial cellular processes...
7.
Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II
Steurer B, Janssens R, Geverts B, Geijer M, Wienholz F, Theil A, et al.
Proc Natl Acad Sci U S A . 2018 Apr; 115(19):E4368-E4376. PMID: 29632207
Initiation and promoter-proximal pausing are key regulatory steps of RNA Polymerase II (Pol II) transcription. To study the in vivo dynamics of endogenous Pol II during these steps, we generated...