Marion A H Feijge
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Explore the profile of Marion A H Feijge including associated specialties, affiliations and a list of published articles.
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39
Citations
810
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Recent Articles
1.
Swieringa F, Solari F, Pagel O, Beck F, Huang J, Feijge M, et al.
Sci Rep
. 2020 Jul;
10(1):11389.
PMID: 32647264
Patients diagnosed with pseudohypoparathyroidism type Ia (PHP Ia) suffer from hormonal resistance and abnormal postural features, in a condition classified as Albright hereditary osteodystrophy (AHO) syndrome. This syndrome is linked...
2.
Baaten C, Meacham S, de Witt S, Feijge M, Adams D, Akkerman J, et al.
Blood
. 2018 Oct;
132(24):e35-e46.
PMID: 30275110
Antithrombotic therapies reduce cardiovascular diseases by preventing arterial thrombosis and thromboembolism, but at expense of increased bleeding risks. Arterial thrombosis studies using genetically modified mice have been invaluable for identification...
3.
Baaten C, Swieringa F, Misztal T, Mastenbroek T, Feijge M, Bock P, et al.
Blood Adv
. 2018 Sep;
2(18):2320-2331.
PMID: 30232085
The platelet receptors glycoprotein Ibα (GPIbα) and GPVI are known to be cleaved by members of a disintegrin and metalloprotease (ADAM) family (ADAM10 and ADAM17), but the mechanisms and consequences...
4.
Thomassen S, Mastenbroek T, Swieringa F, Winckers K, Feijge M, Schrijver R, et al.
Thromb Haemost
. 2018 Feb;
118(3):502-513.
PMID: 29452445
Tissue factor pathway inhibitor-alpha (TFPI-α) is a Kunitz-type serine protease inhibitor, which suppresses coagulation by inhibiting the tissue factor (TF)/factor VIIa complex as well as factor Xa. In static plasma-phospholipid...
5.
Mastenbroek T, Feijge M, Kremers R, Bosch M, Swieringa F, De Groef L, et al.
Arterioscler Thromb Vasc Biol
. 2015 Oct;
35(12):2554-61.
PMID: 26471268
Objective: Platelets are increasingly implicated in processes beyond hemostasis and thrombosis, such as vascular remodeling. Members of the matrix metalloproteinase (MMP) family not only remodel the extracellular matrix but also...
6.
Kuijpers M, van der Meijden P, Feijge M, Mattheij N, May F, Govers-Riemslag J, et al.
Arterioscler Thromb Vasc Biol
. 2014 May;
34(8):1674-80.
PMID: 24855058
Objective: Atherothrombosis is the main cause of myocardial infarction and ischemic stroke. Although the extrinsic (tissue factor-factor VIIa [FVIIa]) pathway is considered as a major trigger of coagulation in atherothrombosis,...
7.
Acid sphingomyelinase regulates platelet cell membrane scrambling, secretion, and thrombus formation
Munzer P, Borst O, Walker B, Schmid E, Feijge M, Cosemans J, et al.
Arterioscler Thromb Vasc Biol
. 2013 Nov;
34(1):61-71.
PMID: 24233488
Objective: Platelet activation is essential for primary hemostasis and acute thrombotic vascular occlusions. On activation, platelets release their prothrombotic granules and expose phosphatidylserine, thus fostering thrombin generation and thrombus formation....
8.
van der Meijden P, Bouman A, Feijge M, Van Oerle R, Spronk H, Hamulyak K, et al.
PLoS One
. 2013 Jun;
8(5):e64112.
PMID: 23724024
Background: Recurrent bleeding can complicate the treatment of thrombosis patients with vitamin K antagonists (VKA), even at a well-regulated level of anticoagulation. In this proof-of-principle study, we investigated whether alterations...
9.
Nergiz-Unal R, Kuijpers M, de Witt S, Heeneman S, Feijge M, Garcia Caraballo S, et al.
Thromb Res
. 2013 Jan;
131(5):411-7.
PMID: 23347681
Introduction: Consumption of n-3 polyunsaturated fatty acids (PUFA) and antioxidant polyphenols is considered to decline the risk of cardiovascular disease. Materials And Methods: To provide an explanation for this cardioprotective...
10.
van Kruchten R, Mattheij N, Saunders C, Feijge M, Swieringa F, Wolfs J, et al.
Blood
. 2013 Jan;
121(10):1850-7.
PMID: 23303820
Scott syndrome, a bleeding disorder caused by defective phospholipid scrambling, has been associated with mutations in the TMEM16F gene. The role of TMEM16F in apoptosis- or agonist-induced phosphatidylserine (PS) exposure...