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Mario Seres

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Articles 21
Citations 264
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Recent Articles
11.
Pavlikova L, Seres M, Hano M, Bohacova V, Sevcikova I, Kyca T, et al.
Molecules . 2017 Jul; 22(7). PMID: 28671633
Overexpression of P-glycoprotein (P-gp, drug transporter) in neoplastic cells is the most frequently observed molecular cause of multidrug resistance. Here, we show that the overexpression of P-gp in L1210 cells...
12.
Pavlikova L, Seres M, Imrichova D, Hano M, Rusnak A, Zamorova M, et al.
Gen Physiol Biophys . 2016 Oct; 35(4):497-510. PMID: 27763330
In P-gp-positive cell variants obtained from L1210 cells either by selection with vincristine (L1210/R) or by transfection with the human gene encoding P-gp (L1210/T), we have previously described cross-resistance to...
13.
Messingerova L, Imrichova D, Kavcova H, Seres M, Sulova Z, Breier A
Toxicol In Vitro . 2016 Jul; 36:81-88. PMID: 27396688
We established an azacytidine (AzaC)-resistant human acute myeloid leukemia (AML) cell line (SKM-1/AzaC) by culturing SKM-1 cells in the presence of increasing amounts of AzaC for six months. Because AzaC...
14.
Messingerova L, Jonasova A, Barancik M, Polekova L, Seres M, Gibalova L, et al.
Gen Physiol Biophys . 2015 May; 34(4):399-406. PMID: 26001289
A specific type of myelodysplastic syndrome (MDS) is associated with isolated deletion on the long arm of chromosome 5, i.e., 5q-syndrome (del(5q)). The treatment approaches for MDS del(5q) include the...
15.
Bubencikova T, Cholujova D, Messingerova L, Mislovicova D, Seres M, Breier A, et al.
Int J Mol Sci . 2012 Dec; 13(11):15177-92. PMID: 23203118
P-glycoprotein (P-gp) overexpression is the most frequently observed cause of multidrug resistance in neoplastic cells. In our experiments, P-gp was expressed in L1210 mice leukemia cells (S cells) by selection...
16.
Breier A, Gibalova L, Seres M, Barancik M, Sulova Z
Anticancer Agents Med Chem . 2012 Aug; 13(1):159-70. PMID: 22931413
Multidrug resistance (MDR) of cancer tissue is a phenomenon in which cancer cells exhibit reduced sensitivity to a large group of unrelated drugs with different mechanisms of pharmacological activity. Mechanisms...
17.
Gibalova L, Seres M, Rusnak A, Ditte P, Labudova M, Uhrik B, et al.
Toxicol In Vitro . 2012 Jan; 26(3):435-44. PMID: 22269388
Multidrug resistance (MDR) is a phenomenon in which cells become resistant to cytostatic drugs and other substances with diverse chemical structures and cytotoxicity mechanisms. The most often observed molecular mechanism...
18.
Seres M, Cholujova D, Bubencikova T, Breier A, Sulova Z
Int J Mol Sci . 2011 Dec; 12(11):7772-84. PMID: 22174631
P-glycoprotein (P-gp), also known as ABCB1, is a member of the ABC transporter family of proteins. P-gp is an ATP-dependent drug efflux pump that is localized to the plasma membrane...
19.
Seres M, Ditte P, Breier A, Sulova Z
Gen Physiol Biophys . 2010 Dec; 29(4):396-401. PMID: 21157003
Expression of drug-transporting P-glycoprotein (P-gp, an integral protein of the plasma membrane) in neoplastic cells confers multidrug resistance and also involves alteration of cell sensitivity to inhibitors of the sarco/endoplasmic...
20.
Sulova Z, Ditte P, Kurucova T, Polakova E, Rogozanova K, Gibalova L, et al.
Anticancer Res . 2010 Oct; 30(9):3661-8. PMID: 20944151
Overexpression of P-glycoprotein (P-gp), a plasma membrane drug transporter (ABCB1, a member of the ABC transporter family), is the most prevalent cause of multidrug resistance in cancer tissues. Lectin concanavalin...