Viera Bohacova
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Explore the profile of Viera Bohacova including associated specialties, affiliations and a list of published articles.
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11
Citations
44
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Recent Articles
1.
Kurekova S, Pavlikova L, Seres M, Bohacova V, Spaldova J, Breier A, et al.
Cancer Cell Int
. 2025 Feb;
25(1):35.
PMID: 39920654
In previous research, we revealed that murine leukemia cells L1210 with induced expression of P-glycoprotein (P-gp, a membrane drug transporter, product of the Abcb1 gene) are better able to withstand...
2.
Kyca T, Pavlikova L, Bohacova V, Misak A, Poturnayova A, Breier A, et al.
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34071136
In this paper, we compared the effects of bortezomib on L1210 (S) cells with its effects on P-glycoprotein (P-gp)-positive variant S cells, which expressed P-gp either after selection with vincristine...
3.
Seres M, Pavlikova L, Bohacova V, Kyca T, Borovska I, Lakatos B, et al.
Cells
. 2020 Apr;
9(4).
PMID: 32268491
P-glycoprotein (P-gp, ABCB1 member of the ABC (ATP-binding cassette) transporter family) localized in leukemia cell plasma membranes is known to reduce cell sensitivity to a large but well-defined group of...
4.
Kubickova J, Elefantova K, Pavlikova L, Cagala M, Seres M, Safar P, et al.
Molecules
. 2019 Jun;
24(11).
PMID: 31195716
We describe the screening of a set of cryptopleurine derivatives, namely thienoquinolizidine derivatives and (epi-)benzo analogs with bioactive phenanthroquinolizidine alkaloids that induce cytotoxic effects in the mouse lymphocytic leukemia cell...
5.
Bohacova V, Seres M, Pavlikova L, Kontar S, Cagala M, Bobal P, et al.
Molecules
. 2018 May;
23(5).
PMID: 29723984
The acceleration of drug efflux activity realized by plasma membrane transporters in neoplastic cells, particularly by P-glycoprotein (P-gp, ABCB1 member of the ABC transporter family), represents a frequently observed molecular...
6.
Pavlikova L, Seres M, Hano M, Bohacova V, Sevcikova I, Kyca T, et al.
Molecules
. 2017 Jul;
22(7).
PMID: 28671633
Overexpression of P-glycoprotein (P-gp, drug transporter) in neoplastic cells is the most frequently observed molecular cause of multidrug resistance. Here, we show that the overexpression of P-gp in L1210 cells...
7.
Coculova M, Imrichova D, Seres M, Messingerova L, Bohacova V, Sulova Z, et al.
Leuk Res
. 2016 Aug;
48:32-9.
PMID: 27479651
Multidrug resistance (MDR) is a serious obstacle to the effective chemotherapeutic treatment of leukemia. Expression of plasma membrane P-glycoprotein (P-gp), a transporter involved in drug efflux, is the most frequently...
8.
Hudecova S, Lencesova L, Csaderova L, Sedlak J, Bohacova V, Laukova M, et al.
Gen Physiol Biophys
. 2013 Jul;
32(3):311-23.
PMID: 23817639
Apoptosis induction causes over-expression of the Na+/Ca2+ exchanger of type 1 (NCX1) in the HeLa cell line. During induction of apoptosis and in the presence of isoproterenol hydrochloride (I; β-adrenergic...
9.
Barancik M, Bohacova V, Gibalova L, Sedlak J, Sulova Z, Breier A
Int J Mol Sci
. 2012 Feb;
13(1):369-82.
PMID: 22312258
The drug efflux activity of P-glycoprotein (P-gp, a product of the mdr1 gene, ABCB1 member of ABC transporter family) represents a mechanism by which tumor cells escape death induced by...
10.
Docolomansky P, Bohacova V, Barancik M, Breier A
Gen Physiol Biophys
. 2010 Sep;
29(3):215-21.
PMID: 20817945
There is generally well known that various xanthines occur frequently in natural products, e.g. black coffee, black tea, green tea, natural dyes etc. Xanthine molecules are good tolerated and metabolised...