Zdena Sulova
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Explore the profile of Zdena Sulova including associated specialties, affiliations and a list of published articles.
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39
Citations
336
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Recent Articles
1.
Kurekova S, Pavlikova L, Seres M, Bohacova V, Spaldova J, Breier A, et al.
Cancer Cell Int
. 2025 Feb;
25(1):35.
PMID: 39920654
In previous research, we revealed that murine leukemia cells L1210 with induced expression of P-glycoprotein (P-gp, a membrane drug transporter, product of the Abcb1 gene) are better able to withstand...
2.
Seres M, Spacayova K, Sulova Z, Spaldova J, Breier A, Pavlikova L
Cancers (Basel)
. 2025 Jan;
17(2).
PMID: 39858030
The epidermal growth factor receptor (EGFR) regulates gene expression through two primary mechanisms: as a growth factor in the nucleus, where it translocates upon binding its ligand, or via its...
3.
Bertova A, Kontar S, Ksinanova M, Vergara A, Sulova Z, Breier A, et al.
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769273
Isothiocyanates (ITCs) are naturally occurring sulfur-containing compounds with diverse biological effects. This study investigated the effects of sulforaphane (SFN, an aliphatic ITC) and benzyl isothiocyanate (BITC, an aromatic ITC) on...
4.
Pelegrinova L, Sofrankova L, Spaldova J, Stefik P, Sulova Z, Breier A, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542082
Intracellular calcium, as a second messenger, is involved in multilevel cellular regulatory pathways and plays a role (among other processes) in switching between survival and initiation of cell death in...
5.
Simonicova K, Janotka L, Kavcova H, Sulova Z, Messingerova L, Breier A
Cancers (Basel)
. 2023 Jun;
15(11).
PMID: 37297025
Three AML cell variants (M/A, M/A* from MOLM-13 and S/A from SKM-1) were established for resistance by the same protocol using 5-azacytidine (AZA) as a selection agent. These AZA-resistant variants...
6.
Bertova A, Kontar S, Polozsanyi Z, Simkovic M, Rosenbergova Z, Rebros M, et al.
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142752
The expression of the membrane ABCB1 transporter in neoplastic cells is one of the most common causes of reduced sensitivity to chemotherapy. In our previous study, we investigated the effect...
7.
Simonicova K, Janotka L, Kavcova H, Sulova Z, Breier A, Messingerova L
Drug Resist Updat
. 2022 Mar;
61:100805.
PMID: 35227933
Resistance to the hypomethylating agents (HMAs) 5-azacytidine (AZA) and 5-aza-2'-deoxycytidine (DAC) represents a major obstacle in the treatment of elderly patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML)...
8.
Pavlikova L, Seres M, Breier A, Sulova Z
Cancers (Basel)
. 2022 Feb;
14(4).
PMID: 35205839
Cancer chemotherapy may induce a multidrug resistance (MDR) phenotype. The development of MDR is based on various molecular causes, of which the following are very common: induction of ABC transporter...
9.
Kocibalova Z, Guzyova M, Borovska I, Messingerova L, Copakova L, Sulova Z, et al.
Cancers (Basel)
. 2021 Jul;
13(14).
PMID: 34298843
P-glycoprotein (known as ABCB1 transporter) expression in myeloid blasts of acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) leads to the commonly observed multidrug resistance. Overexpression of latrophilin-1 was detected...
10.
Kyca T, Pavlikova L, Bohacova V, Misak A, Poturnayova A, Breier A, et al.
Int J Mol Sci
. 2021 Jun;
22(11).
PMID: 34071136
In this paper, we compared the effects of bortezomib on L1210 (S) cells with its effects on P-glycoprotein (P-gp)-positive variant S cells, which expressed P-gp either after selection with vincristine...