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Mario Nicodemi

Explore the profile of Mario Nicodemi including associated specialties, affiliations and a list of published articles. Areas
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Articles 91
Citations 2371
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Recent Articles
1.
Fontana A, Bianco S, Tafuri F, Esposito A, Abraham A, Conte M, et al.
J Chem Phys . 2025 Jan; 162(1). PMID: 39745153
In the last years, it has been proved that some viruses are able to re-structure chromatin organization and alter the epigenomic landscape of the host genome. In addition, they are...
2.
Vercellone F, Chiariello A, Esposito A, Conte M, Abraham A, Fontana A, et al.
Physiology (Bethesda) . 2024 Nov; 40(3). PMID: 39601793
The spatial organization of chromatin within the eukaryotic nucleus is critical in regulating key cellular functions, such as gene expression, and its disruption can lead to disease. Advances in experimental...
3.
Dekker J, Oksuz B, Zhang Y, Wang Y, Minsk M, Kuang S, et al.
bioRxiv . 2024 Nov; PMID: 39484446
The dynamic three-dimensional (3D) organization of the human genome (the "4D Nucleome") is closely linked to genome function. Here, we integrate a wide variety of genomic data generated by the...
4.
Conte M, Abraham A, Esposito A, Yang L, Gibcus J, Parsi K, et al.
Int J Mol Sci . 2024 Sep; 25(18). PMID: 39337699
Here, we employ polymer physics models of chromatin to investigate the 3D folding of a 2 Mb wide genomic region encompassing the human gene, a crucial DNA locus involved in...
5.
Conte M, Abraham A, Esposito A, Yang L, Gibcus J, Parsi K, et al.
bioRxiv . 2024 Jul; PMID: 39071404
Here, we employ polymer physics models of chromatin to investigate the 3D folding of a 2Mb wide genomic region encompassing the human gene, a crucial DNA locus involved in key...
6.
Szabo D, Franke V, Bianco S, Batiuk M, Paul E, Kukalev A, et al.
bioRxiv . 2024 May; PMID: 38766140
Midbrain dopamine neurons (DNs) respond to a first exposure to addictive drugs and play key roles in chronic drug usage. As the synaptic and transcriptional changes that follow an acute...
7.
Irastorza-Azcarate I, Kukalev A, Kempfer R, Thieme C, Mastrobuoni G, Markowski J, et al.
bioRxiv . 2024 May; PMID: 38766012
Genetic variation and 3D chromatin structure have major roles in gene regulation. Due to challenges in mapping chromatin conformation with haplotype-specific resolution, the effects of genetic sequence variation on 3D...
8.
Chiariello A, Abraham A, Bianco S, Esposito A, Fontana A, Vercellone F, et al.
Nat Commun . 2024 May; 15(1):4014. PMID: 38740770
SARS-CoV-2 can re-structure chromatin organization and alter the epigenomic landscape of the host genome, but the mechanisms that produce such changes remain unclear. Here, we use polymer physics to investigate...
9.
Pourmorady A, Bashkirova E, Chiariello A, Belagzhal H, Kodra A, Duffie R, et al.
Nature . 2023 Dec; 625(7993):181-188. PMID: 38123679
Olfactory receptor (OR) choice provides an extreme example of allelic competition for transcriptional dominance, where every olfactory neuron stably transcribes one of approximately 2,000 or more OR alleles. OR gene...
10.
Chiariello A, Abraham A, Bianco S, Esposito A, Vercellone F, Conte M, et al.
bioRxiv . 2023 Aug; PMID: 37546924
SARS-CoV-2 is able to re-structure chromatin organization and alters the epigenomic landscape of the host genome, though the mechanisms that produce such changes are still poorly understood. Here, we investigate...