Mariko Okada-Hatakeyama
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Explore the profile of Mariko Okada-Hatakeyama including associated specialties, affiliations and a list of published articles.
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46
Citations
2854
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Recent Articles
1.
Masuda M, Iida K, Iwabuchi S, Tanaka M, Kubota S, Uematsu H, et al.
Am J Pathol
. 2023 Dec;
194(3):415-429.
PMID: 38103888
Small-cell neuroendocrine carcinoma (SCNEC) of the cervix is a rare disease characterized by a high incidence of mixed tumors with other types of cancer. The mechanism underlying this mixed phenotype...
2.
Taniue K, Oda T, Hayashi T, Kamoshida Y, Takeda Y, Sugawara A, et al.
PNAS Nexus
. 2023 Jul;
2(7):pgad220.
PMID: 37448957
Mammalian genomes encode large number of long noncoding RNAs (lncRNAs) that play key roles in various biological processes, including proliferation, differentiation, and stem cell pluripotency. Recent studies have addressed that...
3.
Miyauchi K, Ki S, Ukai M, Suzuki Y, Inoue K, Suda W, et al.
Front Immunol
. 2021 Dec;
12:663177.
PMID: 34867936
Dominant-negative mutations associated with signal transducer and activator of transcription 3 (STAT3) signaling, which controls epithelial proliferation in various tissues, lead to atopic dermatitis in hyper IgE syndrome. This dermatitis...
4.
Michida H, Imoto H, Shinohara H, Yumoto N, Seki M, Umeda M, et al.
Cell Rep
. 2020 Jun;
31(9):107724.
PMID: 32492432
NF-κB is a transcription factor that activates super enhancers (SEs) and typical enhancers (TEs) and triggers threshold and graded gene expression, respectively. However, the mechanisms by which NF-κB selectively participates...
5.
Mino T, Iwai N, Endo M, Inoue K, Akaki K, Hia F, et al.
Nucleic Acids Res
. 2019 Jul;
47(16):8838-8859.
PMID: 31329944
Regnase-1-mediated mRNA decay (RMD), in which inflammatory mRNAs harboring specific stem-loop structures are degraded, is a critical part of proper immune homeostasis. Prior to initial translation, Regnase-1 associates with target...
6.
Morita M, Siddiqui N, Katsumura S, Rouya C, Larsson O, Nagashima T, et al.
Proc Natl Acad Sci U S A
. 2019 Mar;
116(16):7973-7981.
PMID: 30926667
Whole-body metabolic homeostasis is tightly controlled by hormone-like factors with systemic or paracrine effects that are derived from nonendocrine organs, including adipose tissue (adipokines) and liver (hepatokines). Fibroblast growth factor...
7.
Cortes E, Lachowski D, Robinson B, Sarper M, Teppo J, Thorpe S, et al.
EMBO Rep
. 2018 Dec;
20(1).
PMID: 30538116
The tumor microenvironment is fundamental to cancer progression, and the influence of its mechanical properties is increasingly being appreciated. Tamoxifen has been used for many years to treat estrogen-positive breast...
8.
Liu R, Wang J, Ukai M, Sewon K, Chen P, Suzuki Y, et al.
J Mol Cell Biol
. 2018 Nov;
11(8):649-664.
PMID: 30383247
Acquired drug resistance is the major reason why patients fail to respond to cancer therapies. It is a challenging task to determine the tipping point of endocrine resistance and detect...
9.
Galipon J, Ishii R, Ishiguro S, Suzuki Y, Kondo S, Okada-Hatakeyama M, et al.
Methods Mol Biol
. 2018 Jul;
1823:167-183.
PMID: 29959681
Paired-end RNA sequencing (RNA-seq) is usually applied to the quantification of long transcripts such as messenger or long non-coding RNAs, in which case overlapping pairs are discarded. In contrast, RNA-seq...
10.
Ishiguro S, Galipon J, Ishii R, Suzuki Y, Kondo S, Okada-Hatakeyama M, et al.
RNA Biol
. 2018 Jun;
15(7):976-989.
PMID: 29950133
Adenosine deaminases acting on RNA (ADARs) catalyze the deamination of adenosine (A) to inosine (I). A-to-I RNA editing targets double-stranded RNA (dsRNA), and increases the complexity of gene regulation by...