Marija Vuckovic
Overview
Explore the profile of Marija Vuckovic including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
824
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0
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Recent Articles
1.
Sverak H, Yaeger L, Worrall L, Vacariu C, Glenwright A, Vuckovic M, et al.
Nat Commun
. 2024 Nov;
15(1):9936.
PMID: 39548104
Bacteria invest significant resources into the continuous creation and tailoring of their essential protective peptidoglycan (PG) cell wall. Several soluble PG biosynthesis products in the periplasm are transported to the...
2.
Kenward C, Vuckovic M, Paetzel M, Strynadka N
J Biol Chem
. 2024 May;
300(6):107367.
PMID: 38750796
The main protease (M) remains an essential therapeutic target for COVID-19 post infection intervention given its critical role in processing the majority of viral proteins encoded by the genome of...
3.
Perez-Vargas J, Worrall L, Olmstead A, Ton A, Lee J, Villanueva I, et al.
Emerg Microbes Infect
. 2023 Aug;
12(2):2246594.
PMID: 37555275
Antivirals with broad coronavirus activity are important for treating high-risk individuals exposed to the constantly evolving SARS-CoV-2 variants of concern (VOCs) as well as emerging drug-resistant variants. We developed and...
4.
Yu H, Worrall L, Berger T, Petric M, Lin B, Vuckovic M, et al.
J Immunol
. 2023 Jul;
211(6):981-993.
PMID: 37493438
Current vaccine efforts to combat SARS-CoV-2 are focused on the whole spike protein administered as mRNA, viral vector, or protein subunit. However, the SARS-CoV-2 receptor-binding domain (RBD) is the immunodominant...
5.
Garland O, Ton A, Moradi S, Smith J, Kovacic S, Ng K, et al.
J Chem Inf Model
. 2023 Mar;
63(7):2158-2169.
PMID: 36930801
The rapid global spread of the SARS-CoV-2 virus facilitated the development of novel direct-acting antiviral agents (DAAs). The papain-like protease (PLpro) has been proposed as one of the major SARS-CoV-2...
6.
Alexander J, Worrall L, Hu J, Vuckovic M, Satishkumar N, Poon R, et al.
Nature
. 2023 Jan;
613(7943):375-382.
PMID: 36599987
Broad-spectrum β-lactam antibiotic resistance in Staphylococcus aureus is a global healthcare burden. In clinical strains, resistance is largely controlled by BlaR1, a receptor that senses β-lactams through the acylation of...
7.
Lee J, Kenward C, Worrall L, Vuckovic M, Gentile F, Ton A, et al.
Nat Commun
. 2022 Sep;
13(1):5196.
PMID: 36057636
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19, produces polyproteins 1a and 1ab that contain, respectively, 11 or 16 non-structural proteins (nsp). Nsp5 is the main...
8.
Lee J, Worrall L, Vuckovic M, Rosell F, Gentile F, Ton A, et al.
Nat Commun
. 2020 Nov;
11(1):5877.
PMID: 33208735
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the pathogen that causes the disease COVID-19, produces replicase polyproteins 1a and 1ab that contain, respectively, 11 or 16 nonstructural proteins (nsp). Nsp5...
9.
Majewski D, Okon M, Heinkel F, Robb C, Vuckovic M, McIntosh L, et al.
Structure
. 2020 Sep;
29(2):125-138.e5.
PMID: 32877645
The type III secretion system (T3SS) is a multi-membrane-spanning protein channel used by Gram-negative pathogenic bacteria to secrete effectors directly into the host cell cytoplasm. In the many species reliant...
10.
Hu J, Worrall L, Vuckovic M, Hong C, Deng W, Atkinson C, et al.
Nat Microbiol
. 2019 Aug;
4(11):2010-2019.
PMID: 31427728
The bacterial injectisome is a syringe-shaped macromolecular nanomachine utilized by many pathogenic Gram-negative bacteria, including the causative agents of plague, typhoid fever, whooping cough, sexually transmitted infections and major nosocomial...