Marie Winther-Sorensen
Overview
Explore the profile of Marie Winther-Sorensen including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
436
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Recent Articles
1.
Bomholt A, Johansen C, Galsgaard K, Elmelund E, Winther-Sorensen M, Holst J, et al.
Am J Physiol Renal Physiol
. 2024 Sep;
327(5):F712-F724.
PMID: 39265079
The underlying causes of diabetic kidney disease are still largely unknown. New insights into the contributing causes of diabetic nephropathy are important to prevent this complication. Hyperglycemia and hypertension are...
2.
Kjeldsen S, Werge M, Grandt J, Richter M, Thing M, Hetland L, et al.
Am J Physiol Gastrointest Liver Physiol
. 2024 Aug;
327(4):G558-G570.
PMID: 39104323
Increased plasma concentrations of glucagon (hyperglucagonemia) are reported in patients with type 2 diabetes (T2D) and are considered a diabetogenic risk factor. Emerging evidence suggests that hepatic steatosis in obesity...
3.
Winther-Sorensen M, Garcia S, Bartholdy A, Ottenheijm M, Banasik K, Brunak S, et al.
Diabetologia
. 2024 May;
67(8):1602-1615.
PMID: 38705923
Aims/hypotheses: Glucagon and glucagon-like peptide-1 (GLP-1) are derived from the same precursor; proglucagon, and dual agonists of their receptors are currently being explored for the treatment of obesity and metabolic...
4.
Richter M, Kemp I, Heeboll S, Winther-Sorensen M, Kjeldsen S, Jensen N, et al.
Metabolism
. 2024 Apr;
156:155915.
PMID: 38631460
Introduction: Glucagon receptor agonism is currently explored for the treatment of obesity and metabolic dysfunction-associated steatotic liver disease (MASLD). The metabolic effects of glucagon receptor agonism may in part be...
5.
Winther-Sorensen M, Kemp I, Bisgaard H, Holst J, Wewer Albrechtsen N
J Vis Exp
. 2023 Oct;
(200).
PMID: 37870361
The liver has numerous functions, including nutrient metabolism. In contrast to other in vitro and in vivo models of liver research, the isolated perfused liver allows the study of liver...
6.
Jensen A, Winther-Sorensen M, Burisch J, Bergquist A, Ytting H, Gluud L, et al.
Liver Int
. 2023 Sep;
43(11):2479-2491.
PMID: 37752719
Background And Aims: Patients with some chronic liver diseases have increased risk of diabetes. Whether this is also the case for patients with autoimmune liver diseases is unknown. The study...
7.
Jensen A, Ytting H, Winther-Sorensen M, Burisch J, Bergquist A, Gluud L, et al.
Eur J Gastroenterol Hepatol
. 2023 Jul;
35(9):938-947.
PMID: 37505973
Autoimmune liver diseases include autoimmune hepatitis, primary biliary cholangitis, and primary sclerosing cholangitis. They are chronic, heterogenous diseases affecting the liver which is a key metabolic organ that ensures glucose...
8.
Bomholt A, Johansen C, Christensen J, Kjeldsen S, Galsgaard K, Winther-Sorensen M, et al.
Commun Biol
. 2022 Nov;
5(1):1278.
PMID: 36418521
Glucagon is a major regulator of metabolism and drugs targeting the glucagon receptor (GCGR) are being developed. Insight into tissue and cell-specific expression of the GCGR is important to understand...
9.
Galsgaard K, Elmelund E, Johansen C, Bomholt A, Kizilkaya H, Ceutz F, et al.
Mol Metab
. 2022 Nov;
66:101639.
PMID: 36400402
Objective: Treatment with glucagon receptor antagonists (GRAs) reduces blood glucose but causes dyslipidemia and accumulation of fat in the liver. We investigated the acute and chronic effects of glucagon on...
10.
Winther-Sorensen M, Holst J, Wewer Albrechtsen N
Curr Opin Lipidol
. 2022 Nov;
34(1):27-31.
PMID: 36373738
Purpose Of Review: Glucagon increases hepatic glucose production and in patients with metabolic diseases, glucagon secretion is increased contributing to diabetic hyperglycemia. This review explores the role of amino acids...