Marie McIlroy
Overview
Explore the profile of Marie McIlroy including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
335
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0
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Recent Articles
1.
Kavanagh D, McIlroy M, Myers E, Bane F, Crotty T, McDermott E, et al.
Endocr Relat Cancer
. 2024 Nov;
31(12).
PMID: 39591753
No abstract available.
2.
Tomkins M, McDonnell T, Cussen L, Sagmeister M, Oestlund I, Shaheen F, et al.
J Clin Endocrinol Metab
. 2024 Oct;
PMID: 39382395
Context: 11-oxygenated androgens are a group of adrenal-derived steroids that require peripheral activation. In vitro data highlight a putative role for 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) in 11-oxygenated androgen biosynthesis,...
3.
Miller C, Madden-Doyle L, Jayasena C, McIlroy M, Sherlock M, OReilly M
Eur J Endocrinol
. 2024 Sep;
191(6):R1-R17.
PMID: 39344641
Hypogonadism in men is associated with an adverse metabolic phenotype and increased mortality. Reciprocally, obesity and insulin resistance can suppress the hypothalamic-pituitary-gonadal axis in the absence of structural organic disease,...
4.
Agbana S, McIlroy M
J Steroid Biochem Mol Biol
. 2024 Jun;
243:106559.
PMID: 38823459
Steroid hormone receptors are key mediators in the execution of hormone action through a combination of genomic and non-genomic action. Since their isolation and characterisation in the early 20th Century...
5.
McDonnell T, Cussen L, McIlroy M, OReilly M
Ther Adv Endocrinol Metab
. 2022 Jul;
13:20420188221113140.
PMID: 35874313
Polycystic ovary syndrome (PCOS) is the most common endocrine condition affecting women. It has traditionally been viewed as a primarily reproductive disorder; however, it is increasingly recognized as a lifelong...
6.
Bleach R, Madden S, Hawley J, Charmsaz S, Selli C, Sheehan K, et al.
Clin Cancer Res
. 2021 May;
27(14):3980-3989.
PMID: 34016642
Purpose: There is strong epidemiologic evidence indicating that estrogens may not be the sole steroid drivers of breast cancer. We hypothesize that abundant adrenal androgenic steroid precursors, acting via the...
7.
Bleach R, Sherlock M, OReilly M, McIlroy M
Front Cell Dev Biol
. 2021 Apr;
9:630503.
PMID: 33816477
To date, almost all solid malignancies have implicated insulin-like growth factor (IGF) signalling as a driver of tumour growth. However, the remarkable level of crosstalk between sex hormones, the IGF-1...
8.
Creevey L, Bleach R, Madden S, Toomey S, Bane F, Vareslija D, et al.
Mol Cancer Ther
. 2019 Jul;
18(10):1731-1743.
PMID: 31289138
Divergent roles for androgen receptor (AR) in breast cancer have been reported. Following aromatase inhibitor (AI) treatment, the conversion of circulating androgens into estrogens can be diminished by >99%. We...
9.
Bleach R, McIlroy M
Front Endocrinol (Lausanne)
. 2018 Nov;
9:594.
PMID: 30416486
Androgen receptor (AR) is the most widely expressed steroid receptor protein in normal breast tissue and is detectable in approximately 90% of primary breast cancers and 75% of metastatic lesions....
10.
Charmsaz S, Hughes E, Bane F, Tibbitts P, McIlroy M, Byrne C, et al.
BMC Med
. 2017 Apr;
15(1):79.
PMID: 28399921
Background: Endocrine therapy is standard treatment for estrogen receptor (ER)-positive breast cancer. However, its efficacy is limited by intrinsic and acquired resistance. Here the potential of S100β as a biomarker...