Marie Le Bouteiller
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Explore the profile of Marie Le Bouteiller including associated specialties, affiliations and a list of published articles.
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10
Citations
96
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Recent Articles
1.
Wang J, Sadeghi C, Le L, Le Bouteiller M, Frock R
Sci Adv
. 2024 Jul;
10(31):eadn4682.
PMID: 39083600
G-G phase alternative end joining (A-EJ) is a recently defined mutagenic pathway characterized by resected deletion and translocation joints that are predominantly direct and are distinguished from A-EJ in cycling...
2.
Barghouth P, Melemenidis S, Montay-Gruel P, Ollivier J, Viswanathan V, Jorge P, et al.
Radiother Oncol
. 2023 Sep;
188:109906.
PMID: 37690668
Background And Purpose: The impact of radiotherapy (RT) at ultra high vs conventional dose rate (FLASH vs CONV) on the generation and repair of DNA double strand breaks (DSBs) is...
3.
Barghouth P, Melemenidis S, Montay-Gruel P, Ollivier J, Viswanathan V, Jorge P, et al.
bioRxiv
. 2023 Apr;
PMID: 37034651
The molecular and cellular mechanisms driving the enhanced therapeutic ratio of ultra-high dose-rate radiotherapy (FLASH-RT) over slower conventional (CONV-RT) radiotherapy dose-rate remain to be elucidated. However, attenuated DNA damage and...
4.
Schweiger P, Le Bouteiller M, Yui S, Thodberg M, Clement D, Jensen K
Gastroenterology
. 2022 Aug;
163(6):1688-1690.e3.
PMID: 36037993
No abstract available.
5.
Liang Z, Kumar V, Le Bouteiller M, Zurita J, Kenrick J, Lin S, et al.
Proc Natl Acad Sci U S A
. 2021 May;
118(21).
PMID: 34006647
Classical nonhomologous end joining (C-NHEJ) repairs DNA double-strand breaks (DSBs) throughout interphase but predominates in G1 phase when homologous recombination is unavailable. Complexes containing the Ku70/80 ("Ku") and XRCC4/ligase IV...
6.
Wang Q, Liu J, Janssen J, Le Bouteiller M, Frock R, Goncalves M
Nucleic Acids Res
. 2021 Jan;
49(2):1173-1198.
PMID: 33398349
RNA-guided nucleases (RGNs) based on CRISPR systems permit installing short and large edits within eukaryotic genomes. However, precise genome editing is often hindered due to nuclease off-target activities and the...
7.
Gayraud-Morel B, Le Bouteiller M, Commere P, Cohen-Tannoudji M, Tajbakhsh S
Development
. 2018 Nov;
145(23).
PMID: 30478226
Cell fate decisions occur through the action of multiple factors, including signalling molecules and transcription factors. Recently, the regulation of translation has emerged as an important step for modulating cellular...
8.
Jarzebowski L, Le Bouteiller M, Coqueran S, Raveux A, Vandormael-Pournin S, David A, et al.
RNA
. 2018 Sep;
24(12):1803-1812.
PMID: 30242063
The contribution of basal cellular processes to the regulation of tissue homeostasis has just started to be appreciated. However, our knowledge of the modulation of ribosome biogenesis activity in situ...
9.
Le Bouteiller M, Jensen K
Nat Cell Biol
. 2015 Feb;
17(1):5-6.
PMID: 25679030
Hippo signalling has been associated with many important tissue functions including the regulation of organ size. In the intestinal epithelium differing functions have been proposed for the effectors of Hippo...
10.
Le Bouteiller M, Souilhol C, Beck-Cormier S, Stedman A, Burlen-Defranoux O, Vandormael-Pournin S, et al.
J Exp Med
. 2013 Sep;
210(11):2351-69.
PMID: 24062412
Blood cell production relies on the coordinated activities of hematopoietic stem cells (HSCs) and multipotent and lineage-restricted progenitors. Here, we identify Notchless (Nle) as a critical factor for HSC maintenance...