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Marie Christelle Saade

Explore the profile of Marie Christelle Saade including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 31
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Recent Articles
1.
Suzuki T, Loyde E, Chen S, Etzrodt V, Idowu T, Clark A, et al.
J Clin Invest . 2025 Mar; PMID: 40029709
Elevated Angiopoietin-2 is associated with diverse inflammatory conditions including sepsis, a leading global cause of mortality. During inflammation, Angiopoietin-2 antagonizes the endothelium-enriched receptor Tie2 to destabilize the vasculature. In other...
2.
Alhumaidi R, Huang H, Saade M, Clark A, Parikh S
Trends Mol Med . 2025 Jan; PMID: 39757045
Disturbances in kidney tubular cell metabolism are increasingly recognized as a feature of acute kidney injury (AKI). In AKI, tubular epithelial cells undergo abnormal metabolic shifts that notably disrupt NAD...
3.
Hoteit R, Hassoun A, Bou Sanayeh E, Saade M, Honein-AbouHaidar G, Akl E
Health Res Policy Syst . 2024 Mar; 22(1):38. PMID: 38539218
Background: The coronavirus disease 2019 (COVID-19) pandemic has strained healthcare systems globally, particularly in terms of access to medicines. Lebanon has been greatly affected by the pandemic, having faced concomitant...
4.
Haddad G, Moussalem C, Saade M, Hayek M, Massaad E, Gibbs W, et al.
World Neurosurg . 2024 Mar; 187:133-140. PMID: 38428809
Background: Malignant soft tissue spinal canal tumors compromise 20% of all spinal neoplasms. They may be primary or metastatic lesions, originating from a diverse range of tissues within and surrounding...
5.
Clark A, Saade M, Vemireddy V, Vu K, Flores B, Etzrodt V, et al.
Kidney Int . 2023 Oct; 104(6):1150-1163. PMID: 37783445
Nicotinamide adenine dinucleotide (NAD+) levels decline in experimental models of acute kidney injury (AKI). Attenuated enzymatic conversion of tryptophan to NAD+ in tubular epithelium may contribute to adverse cellular and...
6.
Saade M, Parikh S
Kidney360 . 2023 Aug; 4(8):1014-1016. PMID: 37651663
No abstract available.
7.
Saade M, Clark A, Parikh S
Front Nutr . 2023 Jan; 9:1070435. PMID: 36590198
Introduction: Quinolinic acid is an intermediate compound derived from the metabolism of dietary tryptophan. Its accumulation has been reported in patients suffering a broad spectrum of diseases and conditions. In...
8.
Clark A, Saade M, Parikh S
Semin Nephrol . 2022 Nov; 42(3):151287. PMID: 36411195
Acute kidney injury (AKI) is a serious and highly prevalent disease, yet only supportive treatment is available. Nicotinamide adenine dinucleotide (NAD+) is a cofactor necessary for adenosine triphosphate (ATP) production...
9.
Saade M, Wehbe H, Mourad F, Hosni M, Francis F, Makki M, et al.
Ann Gastroenterol . 2022 Sep; 35(5):503-508. PMID: 36061154
Background: The presence of granulomas in the gastrointestinal (GI) tract is one of the characteristic histologic features of Crohn's disease (CD). The clinical significance of granulomas remains unclear. In this...
10.
Saade M, Kerbage A, Jabak S, Makki M, Barada K, Shaib Y
BMC Gastroenterol . 2022 Jun; 22(1):301. PMID: 35729498
Background/aim: The ABC score is a new pre-endoscopic scoring system that was recently developed to accurately predict one-month mortality in upper and lower gastrointestinal bleeding (GIB). We aim to validate...