Validation of the New ABC Score for Predicting 30-day Mortality in Gastrointestinal Bleeding

Overview

Journal BMC Gastroenterol

Publisher Biomed Central

Specialty Gastroenterology

Date 2022 Jun 21

PMID 35729498

Authors

Marie Christelle Saade

Anthony Kerbage

Suha Jabak

Maha Makki

Kassem Barada

Yasser Shaib

Affiliations

Soon will be listed here.

Abstract

Background/aim: The ABC score is a new pre-endoscopic scoring system that was recently developed to accurately predict one-month mortality in upper and lower gastrointestinal bleeding (GIB). We aim to validate this new score on a cohort of Lebanese patients treated in a tertiary care center and to compare it to currently existing scores.

Methods: Adult patients admitted to the American University of Beirut Medical Center (AUBMC) with overt GIB between January 2013 and August 2020 were included. The area under receiver operating characteristic (AUROC) curves of the ABC score in predicting 30-day mortality was calculated using the SPSS software. Other optimal existing scores for predicting mortality (the Oakland score for lower GIB, the AIMS-65 and the Rockall scores for upper GIB)s were also assessed and compared to the ABC score.

Results: A total of 310 patients were included in our study. For upper GIB, the ABC score showed good performance in predicting 30-day mortality (AUROC: 0.79), outperforming both the AIMS-65 score (AUROC 0.67, p < 0.001) and the Rockall score (AUROC: 0.62, p < 0.001). For lower GIB, the ABC score also had good performance which was comparable to the Oakland score (AUROC: 0.70 vs 0.56, p = 0.26).

Conclusion: In our cohort of patients, the ABC score demonstrated good performance in predicting 30-day mortality for patients with upper and lower GIB compared to other established risk scores, which may help guide management decisions. This simple and novel score provides valuable prognostic information for patients presenting with GIB and appears to be reproducible in different patient populations.

Citing Articles

Reply to Khan et al., Critical Insights: ABC score is a better predictor for 30-day mortality in upper gastrointestinal bleeding: A prospective single-center study.

Pemmada V, Shetty A, Bhat G Indian J Gastroenterol. 2025; .

PMID: 39985702 DOI: 10.1007/s12664-025-01750-2.

ABC score is a better predictor for 30-day mortality in upper gastrointestinal bleeding: A prospective single-center study.

Pemmada V, Shetty A, Shetty S, C G, Musunuri B, Rajpurohit S Indian J Gastroenterol. 2024; .

PMID: 39699753 DOI: 10.1007/s12664-024-01703-1.

Comparison and validation of several scoring systems for non-variceal upper gastrointestinal bleeding: a retrospective study.

In K, Oh Y, Moon H, Jung S, Kang S, Sung J Sci Rep. 2024; 14(1):27940.

PMID: 39537867 PMC: 11561243. DOI: 10.1038/s41598-024-79643-1.

Validating the CHAMPS Score: A Novel and Reliable Prognostic Score of Non-Variceal Upper Gastrointestinal Bleeding.

Lam H, Nguyen T, Bui H, Vo T Clin Exp Gastroenterol. 2024; 17:201-211.

PMID: 39050121 PMC: 11268722. DOI: 10.2147/CEG.S469218.

Predictive Significance of the ABC Score for Early Re-Hemorrhage and In-Hospital Mortality in High-Risk Variceal Bleeding among Cirrhotic Patients.

Ky T, Trang N, Binh M Diagnostics (Basel). 2023; 13(23).

PMID: 38066811 PMC: 10706279. DOI: 10.3390/diagnostics13233570.

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